YONGCHENG SONG to Methyltransferases
This is a "connection" page, showing publications YONGCHENG SONG has written about Methyltransferases.
Connection Strength
2.929
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Synthesis, Structure-Activity Relationships, and Antitumor Activities of Quinoxiline-Containing Inhibitors of the Protein-Protein Interactions between Transcription Coactivator AF9/ENL and DOT1L/AF4. J Med Chem. 2025 Sep 25; 68(18):19396-19414.
Score: 0.916
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Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer. Oncotarget. 2014 Nov 15; 5(21):10665-77.
Score: 0.432
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A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L. J Med Chem. 2013 Nov 27; 56(22):8972-83.
Score: 0.396
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Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L. J Med Chem. 2012 Sep 27; 55(18):8066-74.
Score: 0.371
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Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies. J Am Chem Soc. 2011 Oct 26; 133(42):16746-9.
Score: 0.348
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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81.
Score: 0.121
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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives. J Hematol Oncol. 2016 06 17; 9(1):49.
Score: 0.121
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Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. J Hematol Oncol. 2016 Mar 12; 9:24.
Score: 0.118
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DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy. PLoS One. 2014; 9(5):e98270.
Score: 0.105