"Otosclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formation of spongy bone in the labyrinth capsule which can progress toward the STAPES (stapedial fixation) or anteriorly toward the COCHLEA leading to conductive, sensorineural, or mixed HEARING LOSS. Several genes are associated with familial otosclerosis with varied clinical signs.
| Descriptor ID |
D010040
|
| MeSH Number(s) |
C09.218.768
|
| Concept/Terms |
Otosclerosis- Otosclerosis
- Otoscleroses
- Otospongiosis
- Otospongioses
|
Below are MeSH descriptors whose meaning is more general than "Otosclerosis".
Below are MeSH descriptors whose meaning is more specific than "Otosclerosis".
This graph shows the total number of publications written about "Otosclerosis" by people in this website by year, and whether "Otosclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Otosclerosis" by people in Profiles.
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Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure. Nat Commun. 2023 01 18; 14(1):157.
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Otosclerosis in an Urban Population. Otol Neurotol. 2021 01; 42(1):24-29.
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With the Incidence of Otosclerosis Declining, Should Stapedectomy Remain a Key-Indicator Case for Otolaryngology Residents? Otolaryngol Head Neck Surg. 2020 12; 163(6):1070-1072.
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Insufficient evidence for a role of SERPINF1 in otosclerosis. Mol Genet Genomics. 2019 Aug; 294(4):1001-1006.
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Variants affecting diverse domains of MEPE are associated with two distinct bone disorders, a craniofacial bone defect and otosclerosis. Genet Med. 2019 05; 21(5):1199-1208.
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Genetic association analysis in a clinically and histologically confirmed otosclerosis population confirms association with the TGFB1 gene but suggests an association of the RELN gene with a clinically indistinguishable otosclerosis-like phenotype. Otol Neurotol. 2014 Jul; 35(6):1058-64.
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Rare variants in BMP2 and BMP4 found in otosclerosis patients reduce Smad signaling. Otol Neurotol. 2014 Mar; 35(3):395-400.
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COL1A1 association and otosclerosis: a meta-analysis. Am J Med Genet A. 2012 May; 158A(5):1066-70.
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Commentary on "Otosclerosis: thirty-year follow-up after surgery". Ann Otol Rhinol Laryngol. 2011 Sep; 120(9):615-6.
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Association of COL1A1 and TGFB1 polymorphisms with otosclerosis in a Tunisian population. Ann Hum Genet. 2011 Sep; 75(5):598-604.