"Chromogranin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.
| Descriptor ID |
D053379
|
| MeSH Number(s) |
D12.776.631.199.249
|
| Concept/Terms |
Chromogranin A- Chromogranin A
- Parathyroid Secretory Protein
- Secretory Protein, Parathyroid
- CHGA Protein
- Secretory Protein I, Parathyroid Gland
|
Below are MeSH descriptors whose meaning is more general than "Chromogranin A".
Below are MeSH descriptors whose meaning is more specific than "Chromogranin A".
This graph shows the total number of publications written about "Chromogranin A" by people in this website by year, and whether "Chromogranin A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 2 | 3 |
| 2011 | 5 | 3 | 8 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2016 | 2 | 2 | 4 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chromogranin A" by people in Profiles.
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Circulating Chromogranin A as a Surveillance Biomarker in Patients with Carcinoids-The CASPAR Study. Clin Cancer Res. 2024 Dec 16; 30(24):5559-5567.
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Biomarker response to high-specific-activity I-131 meta-iodobenzylguanidine in pheochromocytoma/paraganglioma. Endocr Relat Cancer. 2023 02 01; 30(2).
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Insulinoma-associated protein 1 immunostaining for various types of neuroendocrine tumors on FNA smears. Cancer Cytopathol. 2020 10; 128(10):725-732.
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Regulation of tumor growth by circulating full-length chromogranin A. Oncotarget. 2016 Nov 08; 7(45):72716-72732.
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Inhibition of chronic lymphocytic leukemia progression by full-length chromogranin A and its N-terminal fragment in mouse models. Oncotarget. 2016 Jul 05; 7(27):41725-41736.
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Utility of chromogranin A, pancreatic polypeptide, glucagon and gastrin in the diagnosis and follow-up of pancreatic neuroendocrine tumours in multiple endocrine neoplasia type 1 patients. Clin Endocrinol (Oxf). 2016 09; 85(3):400-7.
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Neuroendocrine Differentiation in Thymic Carcinomas: A Diagnostic Pitfall: An Immunohistochemical Analysis of 27 Cases. Am J Clin Pathol. 2016 Mar; 145(3):393-400.
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Thymic neuroendocrine tumors (paraganglioma and carcinoid tumors): a comparative immunohistochemical study of 46 cases. Hum Pathol. 2014 Dec; 45(12):2463-70.
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Molecular pathology and genetics of gastrointestinal neuroendocrine tumours. Curr Opin Endocrinol Diabetes Obes. 2014 Feb; 21(1):22-7.
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The effects of long-term therapy with proton pump inhibitors on meal stimulated gastrin. Dig Liver Dis. 2014 Feb; 46(2):125-30.