"Acrosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
Descriptor ID |
D000177
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MeSH Number(s) |
A05.360.490.890.820.100 A11.284.430.214.190.875.190.550.040 A11.497.760.400.100
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acrosome".
Below are MeSH descriptors whose meaning is more specific than "Acrosome".
This graph shows the total number of publications written about "Acrosome" by people in this website by year, and whether "Acrosome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1996 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Acrosome" by people in Profiles.
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PDCL2 is essential for sperm acrosome formation and male fertility in mice. Andrology. 2023 07; 11(5):789-798.
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Exogenous gamma-aminobutyric acid addition enhances porcine sperm acrosome reaction. Anim Sci J. 2022 Jan-Dec; 93(1):e13744.
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FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice. J Cell Sci. 2021 11 01; 134(21).
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The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization. Proc Natl Acad Sci U S A. 2021 09 28; 118(39).
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Mouse t-complex protein 11 is important for progressive motility in sperm?. Biol Reprod. 2020 04 15; 102(4):852-862.
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Identification of KIAA1210 as a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testes. Biol Reprod. 2017 02 01; 96(2):469-477.
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Sperm postacrosomal WW domain-binding protein is not required for mouse egg activation. Biol Reprod. 2015 Oct; 93(4):94.
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Use of immobilized cryopreserved bovine semen in a blind artificial insemination trial. Theriogenology. 2015 Aug; 84(3):413-20.
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SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia. Development. 2012 Oct; 139(19):3583-9.
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Association of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men. Mol Hum Reprod. 2012 Jan; 18(1):14-21.