"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
|
| MeSH Number(s) |
D12.125.072.401.623.270
|
| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
|
Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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Injectable, reversibly thermoresponsive captopril-laden hydrogel for the local treatment of sensory loss in diabetic neuropathy. Sci Rep. 2024 08 16; 14(1):18978.
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Angiotensin-converting enzyme inhibitor nephrotoxicity in neonates with cardiac disease. Pediatr Cardiol. 2014 Mar; 35(3):499-506.
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Effect of certain angiotensin-converting enzyme inhibitors on mortality in heart failure: a multiple-propensity analysis. Res Social Adm Pharm. 2012 Mar-Apr; 8(2):145-56.
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Captopril induced reversible acute renal failure in a premature neonate with double outlet right ventricle and congestive heart failure. World J Pediatr. 2011 Feb; 7(1):89-91.
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Captopril-induced pulmonary infiltrates with eosinophilia in an infant with congenital heart disease. Pediatr Cardiol. 2005 Sep-Oct; 26(5):690-3.
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Angiotensin-receptor blockade in acute myocardial infarction--a matter of dose. N Engl J Med. 2003 Nov 13; 349(20):1963-5.
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Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. Am J Physiol Heart Circ Physiol. 2002 Feb; 282(2):H615-21.
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Observation of high and low molecular weight inhibitors of angiotensin-converting enzyme in rat lung. Arch Int Pharmacodyn Ther. 1996 May-Jun; 331(3):301-12.
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Renovascular hypertension in blacks. Am J Hypertens. 1996 Jan; 9(1):18-23.
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Endogenous BK stimulates ischemically sensitive abdominal visceral C fiber afferents through kinin B2 receptors. Am J Physiol. 1994 Dec; 267(6 Pt 2):H2398-406.