"Aquaporin 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
| Descriptor ID |
D051399
|
| MeSH Number(s) |
D12.776.157.530.400.500.040.437 D12.776.543.550.450.730.040.437 D12.776.543.585.400.730.040.530
|
| Concept/Terms |
Aquaporin 2- Aquaporin 2
- AQP2 Protein
- Water Channel Of Collecting Duct
- Aquaporin-2
- Aquaporin-CD
- Aquaporin CD
|
Below are MeSH descriptors whose meaning is more general than "Aquaporin 2".
Below are MeSH descriptors whose meaning is more specific than "Aquaporin 2".
This graph shows the total number of publications written about "Aquaporin 2" by people in this website by year, and whether "Aquaporin 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Aquaporin 2" by people in Profiles.
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A Case of Iatrogenic Dehydration. Am J Kidney Dis. 2019 09; 74(3):A15-A18.
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Adam10 mediates the choice between principal cells and intercalated cells in the kidney. J Am Soc Nephrol. 2015 Jan; 26(1):149-59.
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Collecting duct principal cell transport processes and their regulation. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):135-46.
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Aqp2-expressing cells give rise to renal intercalated cells. J Am Soc Nephrol. 2013 Feb; 24(2):243-52.
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Functional characterization of three aquaglyceroporins from Trypanosoma brucei in osmoregulation and glycerol transport. Cell Physiol Biochem. 2011; 27(3-4):411-20.
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Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei. J Biol Chem. 2004 Oct 08; 279(41):42669-76.
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Characterization of an aquaporin-2 water channel gene mutation causing partial nephrogenic diabetes insipidus in a Mexican family: evidence of increased frequency of the mutation in the town of origin. J Am Soc Nephrol. 2004 May; 15(5):1223-31.
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Acute effects of vasopressin V2-receptor antagonist on kidney AQP2 expression and subcellular distribution. Am J Physiol. 1998 08; 275(2):F285-97.
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Water channel protein subtype suggests the origin of renal cell carcinoma. J Urol. 1996 Jul; 156(1):291-5.