Cystathionine gamma-Lyase
"Cystathionine gamma-Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyzes the cleavage of cystathionine to yield cysteine, ammonia, and 2-ketobutyrate. EC 4.4.1.1.
| Descriptor ID |
D003542
|
| MeSH Number(s) |
D08.811.520.300.250
|
| Concept/Terms |
Cystathionine gamma-Lyase- Cystathionine gamma-Lyase
- Cystathionine gamma Lyase
- gamma-Lyase, Cystathionine
- Cystine Desulfhydrase
- Desulfhydrase, Cystine
- Cysteine Desulfhydrase
- Desulfhydrase, Cysteine
- gamma-Cystathionase
- gamma Cystathionase
- Homoserine Deaminase
- Deaminase, Homoserine
- Homoserine Dehydratase
- Dehydratase, Homoserine
- Cystathionase
- Cystine Desulfohydrolase
- Desulfohydrolase, Cystine
|
Below are MeSH descriptors whose meaning is more general than "Cystathionine gamma-Lyase".
Below are MeSH descriptors whose meaning is more specific than "Cystathionine gamma-Lyase".
This graph shows the total number of publications written about "Cystathionine gamma-Lyase" by people in this website by year, and whether "Cystathionine gamma-Lyase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cystathionine gamma-Lyase" by people in Profiles.
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Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine ?-lyase-dependent manner. Nat Commun. 2021 03 19; 12(1):1745.
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The endogenous hydrogen sulfide generating system regulates ovulation. Free Radic Biol Med. 2019 07; 138:43-52.
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Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis. Circulation. 2013 Jun 25; 127(25):2523-34.
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H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science. 2008 Oct 24; 322(5901):587-90.
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Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries. Am J Pathol. 2007 Apr; 170(4):1406-14.
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Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat. Diabetes. 1998 Dec; 47(12):1967-70.