Pulmonary Surfactant-Associated Protein A
"Pulmonary Surfactant-Associated Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
Descriptor ID |
D037662
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MeSH Number(s) |
D12.776.503.280.249.600 D12.776.823.100
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein A".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein A".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein A" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein A" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2005 | 2 | 0 | 2 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein A" by people in Profiles.
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Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest. 2015 Jul 01; 125(7):2808-24.
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Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis. Clin Cancer Res. 2011 Apr 15; 17(8):2434-43.
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Computerized analysis of cytology and fluorescence in situ hybridization (FISH) in induced sputum for lung cancer detection. Cancer Cytopathol. 2010 Oct 25; 118(5):269-77.
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Mechanical ventilation down-regulates surfactant protein A and keratinocyte growth factor expression in premature rabbits. Pediatr Res. 2007 Sep; 62(3):277-82.
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Surfactant protein A gene deletion and prognostics for patients with stage I non-small cell lung cancer. Clin Cancer Res. 2005 Aug 01; 11(15):5417-24.
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Serum KL-6 and surfactant proteins A and D in pediatric interstitial lung disease. Chest. 2005 Jan; 127(1):403-7.
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Immunology of viral respiratory tract infection in infancy. Paediatr Respir Rev. 2003 Jun; 4(2):112-9.