"Angiostatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.
| Descriptor ID |
D043168
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| MeSH Number(s) |
D08.622.610.500 D12.644.276.100.450.500 D12.776.124.790.223.580.500 D12.776.377.715.182.580.500 D12.776.467.100.450.500 D23.529.100.450.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiostatins".
Below are MeSH descriptors whose meaning is more specific than "Angiostatins".
This graph shows the total number of publications written about "Angiostatins" by people in this website by year, and whether "Angiostatins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
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Below are the most recent publications written about "Angiostatins" by people in Profiles.
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Urinary angiostatin, CXCL4 and VCAM-1 as biomarkers of lupus nephritis. Arthritis Res Ther. 2018 01 11; 20(1):6.
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Urine angiostatin and VCAM-1 surpass conventional metrics in predicting elevated renal pathology activity indices in lupus nephritis. Int J Rheum Dis. 2017 Nov; 20(11):1714-1727.
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Systemic lupus erythematosus biomarkers: the challenging quest. Rheumatology (Oxford). 2017 04 01; 56(suppl_1):i32-i45.
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Is Angiostatin Involved in Physiological Foveal Avascularity? Invest Ophthalmol Vis Sci. 2016 09 01; 57(11):4536-52.
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Regulation of angiostatin mobilization by tumor-derived matrix metalloproteinase-2. Methods Mol Med. 2003; 74:375-90.
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Angiostatin inhibits and regresses corneal neovascularization. Arch Ophthalmol. 2002 Aug; 120(8):1063-8.
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Antiangiogenesis -- therapeutic strategies and clinical implications for brain tumors. J Neurooncol. 2000 Oct-Nov; 50(1-2):189-200.
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Urinary proteins with pro-apoptotic and antitumor activity. Apoptosis. 2000 Feb; 5(1):21-8.
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Transforming growth factor-beta 1 inhibits generation of angiostatin by human pancreatic cancer cells. Surgery. 1998 Aug; 124(2):388-93.
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Angiostatin generation by human pancreatic cancer. J Surg Res. 1998 Jun; 77(1):55-8.