cdc42 GTP-Binding Protein
"cdc42 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS. It is associated with a diverse array of cellular functions including cytoskeletal changes, filopodia formation and transport through the GOLGI APPARATUS. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020764
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.700.050 D12.644.360.525.700.050 D12.776.157.325.515.700.050 D12.776.476.525.700.050
|
| Concept/Terms |
cdc42 GTP-Binding Protein- cdc42 GTP-Binding Protein
- GTP-Binding Protein, cdc42
- cdc42 GTP Binding Protein
- p21 cdc42
- cdc42, p21
- cdc42 Protein
- G25K Protein
|
Below are MeSH descriptors whose meaning is more general than "cdc42 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "cdc42 GTP-Binding Protein".
This graph shows the total number of publications written about "cdc42 GTP-Binding Protein" by people in this website by year, and whether "cdc42 GTP-Binding Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 5 | 7 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 2 | 4 |
| 2014 | 1 | 2 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "cdc42 GTP-Binding Protein" by people in Profiles.
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A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function. J Exp Med. 2019 12 02; 216(12):2778-2799.
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miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma. Int J Cancer. 2017 11 15; 141(10):2062-2075.
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Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nat Immunol. 2017 02; 18(2):236-245.
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A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants. Int J Cancer. 2016 11 01; 139(9):2012-20.
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CDC42 inhibition suppresses progression of incipient intestinal tumors. Cancer Res. 2014 Oct 01; 74(19):5480-92.
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Rho GTPases in collective cell migration. Small GTPases. 2014; 5:e28997.
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Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. Mol Cancer Res. 2014 Jun; 12(6):953-64.
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Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice. Gastroenterology. 2013 Oct; 145(4):808-19.
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Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts. Oncogene. 2014 Mar 06; 33(10):1265-73.
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Nebivolol induces distinct changes in profibrosis microRNA expression compared with atenolol, in salt-sensitive hypertensive rats. Hypertension. 2013 May; 61(5):1008-13.