p120 GTPase Activating Protein
"p120 GTPase Activating Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 120-kDa RAS GTPase-activating protein that binds to tyrosine phosphoproteins through its SH2 domains. The 100-kDa RNA-splicing variant (p100 GAP protein) is expressed in placenta.
Descriptor ID |
D020729
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MeSH Number(s) |
D12.644.360.325.150.500.500 D12.776.476.325.150.500.500
|
Concept/Terms |
p120 GTPase Activating Protein- p120 GTPase Activating Protein
- p120rasGAP
- p120 GAP
- GAP, p120
- p125-GAP Protein
- p125 GAP Protein
- p120-GAP Protein
- p120 GAP Protein
- p125 GAP
- GAP, p125
|
Below are MeSH descriptors whose meaning is more general than "p120 GTPase Activating Protein".
Below are MeSH descriptors whose meaning is more specific than "p120 GTPase Activating Protein".
This graph shows the total number of publications written about "p120 GTPase Activating Protein" by people in this website by year, and whether "p120 GTPase Activating Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 2 | 0 | 2 |
2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "p120 GTPase Activating Protein" by people in Profiles.
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Germline genetic mutations in pediatric cerebrovascular anomalies: a multidisciplinary approach to screening, testing, and management. J Neurosurg Pediatr. 2023 03 01; 31(3):212-220.
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Genotypes and phenotypes heterogeneity in PIK3CA-related overgrowth spectrum and overlapping conditions: 150 novel patients and systematic review of 1007 patients with PIK3CA pathogenetic variants. J Med Genet. 2023 02; 60(2):163-173.
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The genetics of vascular birthmarks. Clin Dermatol. 2022 Jul-Aug; 40(4):313-321.
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Germline Loss-of-Function Mutations in EPHB4 Cause a Second Form of Capillary Malformation-Arteriovenous Malformation (CM-AVM2) Deregulating RAS-MAPK Signaling. Circulation. 2017 Sep 12; 136(11):1037-1048.
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RASA1 somatic mutation and variable expressivity in capillary malformation/arteriovenous malformation (CM/AVM) syndrome. Am J Med Genet A. 2016 06; 170(6):1450-4.
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5q14.3 deletion neurocutaneous syndrome: Contiguous gene syndrome caused by simultaneous deletion of RASA1 and MEF2C: A progressive disease. Am J Med Genet A. 2016 Mar; 170(3):688-93.
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The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. Nat Cell Biol. 2015 Jan; 17(1):81-94.
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Angiomotin is a novel component of cadherin-11/?-catenin/p120 complex and is critical for cadherin-11-mediated cell migration. FASEB J. 2015 Mar; 29(3):1080-91.
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Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting. J Clin Invest. 2013 Nov; 123(11):4900-8.
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Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):8621-6.