"Tranylcypromine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)
| Descriptor ID |
D014191
|
| MeSH Number(s) |
D02.092.831.845
|
| Concept/Terms |
Tranylcypromine- Tranylcypromine
- trans-2-Phenylcyclopropylamine
- trans 2 Phenylcyclopropylamine
|
Below are MeSH descriptors whose meaning is more general than "Tranylcypromine".
Below are MeSH descriptors whose meaning is more specific than "Tranylcypromine".
This graph shows the total number of publications written about "Tranylcypromine" by people in this website by year, and whether "Tranylcypromine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tranylcypromine" by people in Profiles.
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Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma. Neuro Oncol. 2015 Nov; 17(11):1463-73.
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Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors. Neuro Oncol. 2011 Aug; 13(8):894-903.
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Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol. 2006 Jun; 13(6):563-7.
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Transdermal selegiline: the new generation of monoamine oxidase inhibitors. CNS Spectr. 2006 May; 11(5):363-75.
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Acute exacerbation of depression after discontinuation of monoamine oxidase inhibitor prior to cardiac surgery. Anesth Analg. 1996 Sep; 83(3):656-7.