"Mexiletine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
| Descriptor ID |
D008801
|
| MeSH Number(s) |
D02.092.831.500 D02.455.426.559.389.657.654.675
|
| Concept/Terms |
KO-1173- KO-1173
- KO 1173
- KO1173
- KOE-1173
- KOE 1173
- KOE1173
|
Below are MeSH descriptors whose meaning is more general than "Mexiletine".
Below are MeSH descriptors whose meaning is more specific than "Mexiletine".
This graph shows the total number of publications written about "Mexiletine" by people in this website by year, and whether "Mexiletine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mexiletine" by people in Profiles.
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Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes. J Med Chem. 2021 05 13; 64(9):5384-5403.
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Thromboelastographic assessment of the impact of mexiletine on coagulation abnormalities induced by air or normal saline intravenous injections in conscious rats. Diving Hyperb Med. 2017 Dec; 47(4):228-232.
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A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents. J Cardiovasc Electrophysiol. 2007 Apr; 18(4):434-40.
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Effect of mexiletine on spinal cord injury dysesthetic pain. Am J Phys Med Rehabil. 1996 Mar-Apr; 75(2):84-7.
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Systemic lidocaine therapy for poststroke pain. South Med J. 1993 Oct; 86(10):1093-6.
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Mexiletine: an effective antiarrhythmic drug for treatment of ventricular arrhythmias in congenital heart disease. J Am Coll Cardiol. 1987 Oct; 10(4):824-9.