"Apomorphine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.
| Descriptor ID |
D001058
|
| MeSH Number(s) |
D03.132.098.038.290 D03.633.100.531.085.030.290 D03.633.400.095.290
|
| Concept/Terms |
Apomorphine Hydrochloride, Anhydrous- Apomorphine Hydrochloride, Anhydrous
- Anhydrous Apomorphine Hydrochloride
- Hydrochloride, Anhydrous Apomorphine
- Apomorphine Hydrochloride Anhydrous
- Anhydrous, Apomorphine Hydrochloride
- Hydrochloride Anhydrous, Apomorphine
Apomorphine Hydrochloride- Apomorphine Hydrochloride
- Hydrochloride, Apomorphine
- Apomorphine Hydrochloride, Hemihydrate
- Hemihydrate Apomorphine Hydrochloride
- Hydrochloride, Hemihydrate Apomorphine
|
Below are MeSH descriptors whose meaning is more general than "Apomorphine".
Below are MeSH descriptors whose meaning is more specific than "Apomorphine".
This graph shows the total number of publications written about "Apomorphine" by people in this website by year, and whether "Apomorphine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apomorphine" by people in Profiles.
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Apomorphine is a potent inhibitor of ferroptosis independent of dopaminergic receptors. Sci Rep. 2024 02 27; 14(1):4820.
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Apomorphine rescues reactive oxygen species-induced apoptosis of fibroblasts with mitochondrial disease. Mitochondrion. 2019 11; 49:111-120.
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Internal pallidal neuronal activity during mild drug-related dyskinesias in Parkinson's disease: decreased firing rates and altered firing patterns. J Neurophysiol. 2007 Apr; 97(4):2627-41.
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Reduced splenic natural killer cell activity in rats with a hyperreactive dopaminergic system. Psychoneuroendocrinology. 2004 Sep; 29(8):1058-64.
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Fetal striatal transplants restore electrophysiological sensitivity to dopamine in the lesioned striatum of rats with experimental Huntington's disease. J Biomed Sci. 2002 Jul-Aug; 9(4):303-10.
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Are dopamine receptor agonists neuroprotective in Parkinson's disease? Drugs Aging. 2001; 18(6):389-96.
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Who believes in "communication"? The Norman Cousins Lecture, 1999. Brain Behav Immun. 2000 Mar; 14(1):2-9.
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A novel sublingual apomorphine treatment for patients with fluctuating Parkinson's disease. Mov Disord. 1999 Jul; 14(4):664-8.
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Efficacy and tolerability of a novel sublingual apomorphine preparation in patients with fluctuating Parkinson's disease. Clin Neuropharmacol. 1999 Jan-Feb; 22(1):1-4.
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Apomorphine-susceptible and apomorphine-unsusceptible Wistar rats differ in their susceptibility to inflammatory and infectious diseases: a study on rats with group-specific differences in structure and reactivity of hypothalamic-pituitary-adrenal axis. J Neurosci. 1997 Apr 01; 17(7):2580-4.