Receptors, Prostaglandin E
"Receptors, Prostaglandin E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors which bind prostaglandins with a high affinity and trigger intracellular changes which influence the behavior of cells. Prostaglandin E receptors prefer prostaglandin E2 to other endogenous prostaglandins. They are subdivided into EP1, EP2, and EP3 types based on their effects and their pharmacology.
| Descriptor ID |
D018078
|
| MeSH Number(s) |
D12.776.543.750.695.200.700.600
|
| Concept/Terms |
Receptors, Prostaglandin E- Receptors, Prostaglandin E
- Prostaglandin E Receptors
- E Receptors, Prostaglandin
- PGE2 Receptors
- PGE Receptor
- PGE Receptors
- Prostaglandin E Receptor
- E Receptor, Prostaglandin
- Receptor, Prostaglandin E
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin E".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin E".
This graph shows the total number of publications written about "Receptors, Prostaglandin E" by people in this website by year, and whether "Receptors, Prostaglandin E" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Prostaglandin E" by people in Profiles.
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TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells. Immunity. 2018 07 17; 49(1):107-119.e4.
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Prostaglandin receptors EP and FP are regulated by estradiol and progesterone in the uterus of ovariectomized rats. Reprod Biol Endocrinol. 2012 Jan 18; 10:3.
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An agonist sensitive, quick and simple cell-based signaling assay for determination of ligands mimicking prostaglandin E2 or E1 activity through subtype EP1 receptor: Suitable for high throughput screening. BMC Complement Altern Med. 2011 Feb 07; 11:11.
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Differential regulation of the aggressive phenotype of inflammatory breast cancer cells by prostanoid receptors EP3 and EP4. Cancer. 2010 Jun 01; 116(11 Suppl):2806-14.
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Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis. FEBS Lett. 2008 Aug 20; 582(19):2863-8.
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Molecular and pharmacological blockade of the EP4 receptor selectively inhibits both proliferation and invasion of human inflammatory breast cancer cells. J Exp Ther Oncol. 2008; 7(4):299-312.
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Cyclooxygenase-2-derived prostaglandin e2 protects mouse embryonic stem cells from apoptosis. Stem Cells. 2007 May; 25(5):1096-103.
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Resolving a case of split personality. Nat Immunol. 2005 May; 6(5):432-4.
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Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion. Endocrinology. 2003 Oct; 144(10):4376-84.
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Decreased expression of tumor necrosis factor-alpha-stimulated gene 6 in cumulus cells of the cyclooxygenase-2 and EP2 null mice. Endocrinology. 2003 Mar; 144(3):1008-19.