Segmental Duplications, Genomic
"Segmental Duplications, Genomic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Low-copy (2-50) repetitive DNA elements that are highly homologous and range in size from 1000 to 400,000 base pairs.
| Descriptor ID |
D056916
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| MeSH Number(s) |
G02.111.570.080.708.565 G05.360.080.708.565
|
| Concept/Terms |
Segmental Duplications, Genomic- Segmental Duplications, Genomic
- Duplication, Genomic Segmental
- Duplications, Genomic Segmental
- Genomic Segmental Duplication
- Genomic Segmental Duplications
- Segmental Duplication, Genomic
- Segmental Duplications
- Duplication, Segmental
- Duplications, Segmental
- Segmental Duplication
Low-Copy Repeats- Low-Copy Repeats
- Low Copy Repeats
- Low-Copy Repeat
- Repeat, Low-Copy
- Repeats, Low-Copy
- Low-Copy Repeats, DNA
- DNA Low-Copy Repeat
- DNA Low-Copy Repeats
- Low Copy Repeats, DNA
- Low-Copy Repeat, DNA
- Repeat, DNA Low-Copy
- Repeats, DNA Low-Copy
- Low-Copy Repeat Sequences
- Low Copy Repeat Sequences
- Low-Copy Repeat Sequence
- Repeat Sequence, Low-Copy
- Repeat Sequences, Low-Copy
- Sequence, Low-Copy Repeat
- Sequences, Low-Copy Repeat
|
Below are MeSH descriptors whose meaning is more general than "Segmental Duplications, Genomic".
Below are MeSH descriptors whose meaning is more specific than "Segmental Duplications, Genomic".
This graph shows the total number of publications written about "Segmental Duplications, Genomic" by people in this website by year, and whether "Segmental Duplications, Genomic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 1 | 2 |
| 2010 | 3 | 1 | 4 |
| 2011 | 3 | 4 | 7 |
| 2012 | 2 | 2 | 4 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Segmental Duplications, Genomic" by people in Profiles.
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PhaseDancer: a novel targeted assembler of segmental duplications unravels the complexity of the human chromosome 2 fusion going from 48 to 46 chromosomes in hominin evolution. Genome Biol. 2023 09 11; 24(1):205.
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The complete sequence of a human Y chromosome. Nature. 2023 Sep; 621(7978):344-354.
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Alu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3. Hum Mol Genet. 2015 Jul 15; 24(14):4061-77.
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Increased genome instability in human DNA segments with self-chains: homology-induced structural variations via replicative mechanisms. Hum Mol Genet. 2013 Jul 01; 22(13):2642-51.
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Inverted low-copy repeats and genome instability--a genome-wide analysis. Hum Mutat. 2013 Jan; 34(1):210-20.
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Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet. 2012; 8(5):e1002692.
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Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation. Cell. 2012 May 11; 149(4):923-35.
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Small rare recurrent deletions and reciprocal duplications in 2q21.1, including brain-specific ARHGEF4 and GPR148. Hum Mol Genet. 2012 Aug 01; 21(15):3345-55.
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Recurrent deletions and reciprocal duplications of 10q11.21q11.23 including CHAT and SLC18A3 are likely mediated by complex low-copy repeats. Hum Mutat. 2012 Jan; 33(1):165-79.
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PTEN genomic deletions that characterize aggressive prostate cancer originate close to segmental duplications. Genes Chromosomes Cancer. 2012 Feb; 51(2):149-60.