7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
7,8,8a,9a-Tetrahydrobenzo(10,11)chryseno (3,4-b)oxirene-7,8-diol. A benzopyrene derivative with carcinogenic and mutagenic activity.
| Descriptor ID |
D015123
|
| MeSH Number(s) |
D02.455.426.559.847.799.306.400.350 D04.615.799.306.400.350
|
| Concept/Terms |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide- 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
- 7,8-Dihydroxy-9,10-Epoxy-7,8,9,10-Tetrahydrobenzo(a)pyrene
- BPDE
- Benzo(a)pyrene 7,8-Dihydrodiol 9,10-Epoxide
- Benzo(a)pyrene-7,8-diol 9,10-Epoxide
- 7,8-BaP-9,10-Diol Epoxide
- Anti-BaPDE
- Anti BaPDE
|
Below are MeSH descriptors whose meaning is more general than "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide".
Below are MeSH descriptors whose meaning is more specific than "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide".
This graph shows the total number of publications written about "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" by people in this website by year, and whether "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 |
| 1997 | 2 | 0 | 2 |
| 1998 | 4 | 1 | 5 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 3 | 1 | 4 |
| 2002 | 1 | 2 | 3 |
| 2003 | 1 | 4 | 5 |
| 2004 | 2 | 0 | 2 |
| 2005 | 2 | 3 | 5 |
| 2007 | 1 | 4 | 5 |
| 2008 | 3 | 0 | 3 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide" by people in Profiles.
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Mutagen sensitivity as measured by induced chromatid breakage as a marker of cancer risk. Methods Mol Biol. 2014; 1105:183-92.
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Correlation between base-excision repair gene polymorphisms and levels of in-vitro BPDE-induced DNA adducts in cultured peripheral blood lymphocytes. PLoS One. 2012; 7(7):e40131.
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Benzo(a)pyrene diol epoxide-induced chromosome 9p21 aberrations are associated with increased risk of bladder cancer. Cancer Epidemiol Biomarkers Prev. 2008 Sep; 17(9):2445-50.
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Genotypes and haplotypes of ERCC1 and ERCC2/XPD genes predict levels of benzo[a]pyrene diol epoxide-induced DNA adducts in cultured primary lymphocytes from healthy individuals: a genotype-phenotype correlation analysis. Carcinogenesis. 2008 Aug; 29(8):1560-6.
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BPDE induced lymphocytic chromosome 3p deletions may predict renal cell carcinoma risk. J Urol. 2008 Jun; 179(6):2416-21.
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In vitro benzo[a]pyrene diol epoxide-induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck. Int J Cancer. 2007 Dec 15; 121(12):2735-40.
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Modulation of DNA damage/DNA repair capacity by XPC polymorphisms. DNA Repair (Amst). 2008 Feb 01; 7(2):141-8.
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Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2065-71.
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Interplay between mutagen sensitivity and epidemiological factors in modulatinglung cancer risk. Int J Cancer. 2007 Jun 15; 120(12):2687-95.
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A modified host-cell reactivation assay to measure repair of alkylating DNA damage for assessing risk of lung adenocarcinoma. Carcinogenesis. 2007 Jul; 28(7):1430-6.