"Cytosine Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE.
| Descriptor ID |
D043525
|
| MeSH Number(s) |
D08.811.277.151.486.625
|
| Concept/Terms |
Cytosine Deaminase- Cytosine Deaminase
- Deaminase, Cytosine
- Cytosine Aminohydrolase
- Aminohydrolase, Cytosine
|
Below are MeSH descriptors whose meaning is more general than "Cytosine Deaminase".
Below are MeSH descriptors whose meaning is more specific than "Cytosine Deaminase".
This graph shows the total number of publications written about "Cytosine Deaminase" by people in this website by year, and whether "Cytosine Deaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cytosine Deaminase" by people in Profiles.
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APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2018 08 22; 10(455).
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Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. Neurosurgery. 2016 Sep; 79(3):481-91.
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Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth. Hum Immunol. 2006 Jan-Feb; 67(1-2):43-6.
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DNA polymerases and somatic hypermutation of immunoglobulin genes. EMBO Rep. 2005 Dec; 6(12):1143-8.
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Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization. Cancer Gene Ther. 2005 Mar; 12(3):284-94.
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Specific gene expression and therapy for pancreatic cancer using the cytosine deaminase gene directed by the rat insulin promoter. J Gastrointest Surg. 2004 Jan; 8(1):98-108; discussion 106-8.
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Basic and clinical immunology. J Allergy Clin Immunol. 2003 Mar; 111(3 Suppl):S813-8.
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Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes. Mol Ther. 2002 Aug; 6(2):287-97.
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Gene therapy for prostate cancer. Expert Rev Anticancer Ther. 2002 Jun; 2(3):309-21.
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High and selective expression of yeast cytosine deaminase under a carcinoembryonic antigen promoter-enhancer. Cancer Res. 2002 Apr 15; 62(8):2337-42.