Malformations of Cortical Development
"Malformations of Cortical Development" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.
| Descriptor ID |
D054220
|
| MeSH Number(s) |
C10.500.507 C16.131.666.507
|
| Concept/Terms |
Malformations of Cortical Development- Malformations of Cortical Development
- Cortical Development Malformation
- Cortical Development Malformations
- Development Malformation, Cortical
- Development Malformations, Cortical
- Malformations of Cerebral Cortex Development
Cortical Dysplasia- Cortical Dysplasia
- Cortical Dysplasias
- Dysplasia, Cortical
- Dysplasias, Cortical
- Cortical Dysplasia, Cerebral
- Cerebral Cortical Dysplasias
- Cortical Dysplasias, Cerebral
- Dysplasia, Cerebral Cortical
- Dysplasias, Cerebral Cortical
- Cerebral Cortical Dysplasia
|
Below are MeSH descriptors whose meaning is more general than "Malformations of Cortical Development".
Below are MeSH descriptors whose meaning is more specific than "Malformations of Cortical Development".
This graph shows the total number of publications written about "Malformations of Cortical Development" by people in this website by year, and whether "Malformations of Cortical Development" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 4 | 1 | 5 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 1 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Malformations of Cortical Development" by people in Profiles.
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Brain Abnormalities in Patients with Germline Variants in H3F3: Novel Imaging Findings and Neurologic Symptoms Beyond Somatic Variants and Brain Tumors. AJNR Am J Neuroradiol. 2022 07; 43(7):1048-1053.
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Limited utility of structural MRI to identify the epileptogenic zone in young children with tuberous sclerosis. J Neuroimaging. 2022 09; 32(5):991-1000.
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Epilepsy surgery in infants up to 3 months of age: Safety, feasibility, and outcomes: A multicenter, multinational study. Epilepsia. 2021 08; 62(8):1897-1906.
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Two cases of DYNC1H1 mutations with intractable epilepsy. Brain Dev. 2021 Sep; 43(8):857-862.
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Cingulate gyrus epilepsy: semiology, invasive EEG, and surgical approaches. Neurosurg Focus. 2020 04 01; 48(4):E8.
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Sociodemographic Factors in Pediatric Epilepsy Surgery. Pediatr Neurol. 2020 06; 107:71-76.
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Severe presentation and complex brain malformations in an individual carrying a CCND2 variant. Mol Genet Genomic Med. 2019 06; 7(6):e708.
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Recurrent mosaic MTOR c.5930C > T (p.Thr1977Ile) variant causing megalencephaly, asymmetric polymicrogyria, and cutaneous pigmentary mosaicism: Case report and review of the literature. Am J Med Genet A. 2019 03; 179(3):475-479.
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Somatic SLC35A2 variants in the brain are associated with intractable neocortical epilepsy. Ann Neurol. 2018 06; 83(6):1133-1146.
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Comprehensive genomic analysis of patients with disorders of cerebral cortical development. Eur J Hum Genet. 2018 08; 26(8):1121-1131.