"Digitonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.
| Descriptor ID |
D004072
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| MeSH Number(s) |
D04.210.500.155.580.130.500.236 D09.408.180.261.236
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Digitonin".
Below are MeSH descriptors whose meaning is more specific than "Digitonin".
This graph shows the total number of publications written about "Digitonin" by people in this website by year, and whether "Digitonin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Digitonin" by people in Profiles.
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Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2. J Biol Chem. 2012 May 11; 287(20):16869-79.
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Specific inhibitors implicate a soluble metalloendoproteinase in exocytosis. Cell Mol Neurobiol. 1987 Dec; 7(4):425-37.
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Use of digitonin fractionation to determine mitochondrial transmembrane ion distribution in cells during anoxia. Anal Biochem. 1985 Apr; 146(1):164-72.
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The subcellular localization of glutaminase isoenzymes in rat kidney cortex. J Biol Chem. 1974 May 25; 249(10):3255-60.
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Localization of glutaminase in rat liver. FEBS Lett. 1973 Dec 01; 37(2):325-8.