"Glutamate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of L-glutamate and water to 2-oxoglutarate and NH3 in the presence of NAD+. (From Enzyme Nomenclature, 1992) EC 1.4.1.2.
| Descriptor ID |
D005969
|
| MeSH Number(s) |
D08.811.682.664.500.398
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glutamate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Glutamate Dehydrogenase".
This graph shows the total number of publications written about "Glutamate Dehydrogenase" by people in this website by year, and whether "Glutamate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutamate Dehydrogenase" by people in Profiles.
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Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes. Oncotarget. 2016 Nov 29; 7(48):79722-79735.
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Chicken liver glutamate dehydrogenase (GDH) demonstrates a histone H3 specific protease (H3ase) activity in vitro. Biochimie. 2013 Nov; 95(11):1999-2009.
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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013 Apr 04; 496(7443):101-5.
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Troglitazone regulates anaplerosis via a pull/push affect on glutamate dehydrogenase mediated glutamate deamination in kidney-derived epithelial cells; implications for the Warburg effect. Cell Physiol Biochem. 2010; 26(4-5):619-28.
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The simultaneous determination of NAD(H) and NADP(H) utilization by glutamate dehydrogenase. Mol Cell Biochem. 2010 Nov; 344(1-2):253-9.
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Systemic activation of glutamate dehydrogenase increases renal ammoniagenesis: implications for the hyperinsulinism/hyperammonemia syndrome. Am J Physiol Endocrinol Metab. 2010 Jun; 298(6):E1219-25.
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On the reversibility of glutamate dehydrogenase and the source of hyperammonemia in the hyperinsulinism/hyperammonemia syndrome. Adv Enzyme Regul. 2010; 50(1):34-43.
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Substrate preferences and glucose uptake in glibenclamide-resistant Leishmania parasites. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Mar-Apr; 140(3-4):395-402.
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Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver. J Ethnopharmacol. 1995 Jul 07; 47(2):69-74.
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Phosphoenolpyruvate carboxykinase is a nuclear enzyme in rats and chickens. Int J Biochem. 1983; 15(12):1473-5.