Adenomatous Polyposis Coli
"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
| Descriptor ID |
D011125
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| MeSH Number(s) |
C04.557.470.035.215.100 C04.588.274.476.411.307.089 C04.700.100 C06.301.371.411.307.090 C06.405.249.411.307.090 C06.405.469.158.356.090 C06.405.469.491.307.090 C06.405.469.578.249 C16.320.700.100
|
| Concept/Terms |
Adenomatous Polyposis Coli- Adenomatous Polyposis Coli
- Adenomatous Polyposis Colus
- Coli, Adenomatous Polyposis
- Colus, Adenomatous Polyposis
- Polyposis Coli, Adenomatous
- Polyposis Colus, Adenomatous
- Polyposis Syndrome, Familial
- Familial Polyposis Syndromes
- Familial Adenomatous Polyposis Coli
- Adenomatous Polyposis Coli, Familial
- Adenomatous Polyposis of the Colon
- Familial Adenomatous Polyposis
- Adenomatous Polyposes, Familial
- Adenomatous Polyposis, Familial
- Familial Adenomatous Polyposes
- Polyposes, Familial Adenomatous
- Polyposis, Familial Adenomatous
- Familial Polyposis Coli
- Familial Adenomatous Polyposis of the Colon
- Familial Multiple Polyposi
- Familial Multiple Polyposus
- Multiple Polyposi, Familial
- Multiple Polyposus, Familial
- Polyposi, Familial Multiple
- Polyposus, Familial Multiple
- Familial Polyposis of the Colon
- Hereditary Polyposis Coli
- Coli, Hereditary Polyposis
- Colus, Hereditary Polyposis
- Hereditary Polyposis Colus
- Polyposis Coli, Hereditary
- Polyposis Colus, Hereditary
- Familial Multiple Polyposis
- Familial Multiple Polyposes
- Multiple Polyposes, Familial
- Multiple Polyposis, Familial
- Polyposes, Familial Multiple
- Polyposis, Familial Multiple
- Familial Multiple Polyposis Syndrome
- Familial Polyposis Syndrome
- Myh-Associated Polyposis
- Myh Associated Polyposis
- Myh-Associated Polyposes
- Polyposes, Myh-Associated
- Polyposis, Myh-Associated
- Polyposis Coli
- Coli, Polyposis
- Colus, Polyposis
- Polyposis Colus
- Polyposis Coli, Familial
- Coli, Familial Polyposis
- Colus, Familial Polyposis
- Familial Polyposis Colus
- Polyposis Colus, Familial
Familial Intestinal Polyposis- Familial Intestinal Polyposis
- Familial Intestinal Polyposes
- Intestinal Polyposes, Familial
- Intestinal Polyposis, Familial
|
Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli".
Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli".
This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in this website by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 4 | 0 | 4 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Adenomatous Polyposis Coli" by people in Profiles.
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Pediatric Cancer Screening in Hereditary Gastrointestinal Cancer Risk Syndromes: An Update from the AACR Childhood Cancer Predisposition Working Group. Clin Cancer Res. 2024 Oct 15; 30(20):4566-4571.
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Large-scale application of ClinGen-InSiGHT APC-specific ACMG/AMP variant classification criteria leads to substantial reduction in VUS. Am J Hum Genet. 2024 Nov 07; 111(11):2427-2443.
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PIGA Mutations and Glycosylphosphatidylinositol Anchor Dysregulation in Polyposis-Associated Duodenal Tumorigenesis. Mol Cancer Res. 2024 06 04; 22(6):515-523.
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Gene-specific ACMG/AMP classification criteria for germline APC variants: Recommendations from the ClinGen InSiGHT Hereditary Colorectal Cancer/Polyposis Variant Curation Expert Panel. Genet Med. 2024 02; 26(2):100992.
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Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer. Cancer Discov. 2022 07 06; 12(7):1702-1717.
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Celecoxib Colorectal Bioavailability and Chemopreventive Response in Patients with Familial Adenomatous Polyposis. Cancer Prev Res (Phila). 2022 04 01; 15(4):217-223.
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Combination of Sulindac and Eflornithine Delays the Need for Lower Gastrointestinal Surgery in Patients With Familial Adenomatous Polyposis: Post Hoc Analysis of a Randomized Clinical Trial. Dis Colon Rectum. 2022 Apr 01; 65(4):536-545.
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SULT1A1 and SULT1A2 Associated Extensive Prolapse-Type Inflammatory Polyposis in Crohn's Colitis. Ann Clin Lab Sci. 2021 Nov; 51(6):868-874.
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NCCN Guidelines? Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021. J Natl Compr Canc Netw. 2021 10 15; 19(10):1122-1132.
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Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis. Cancer Prev Res (Phila). 2021 09; 14(9):851-862.