"beta-Globins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the beta-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 11. They include epsilon-globin, gamma-globin, delta-globin and beta-globin. There is also a pseudogene of beta (theta-beta) in the gene cluster. Adult HEMOGLOBIN is comprised of two ALPHA-GLOBIN chains and two beta-globin chains.
| Descriptor ID |
D055544
|
| MeSH Number(s) |
D12.776.124.400.434.325 D12.776.422.316.762.403.325
|
| Concept/Terms |
beta-Globins- beta-Globins
- beta Globins
- Non-alpha Globin Chain, Unspecified
- Non alpha Globin Chain, Unspecified
- beta-Globin
- beta Globin
|
Below are MeSH descriptors whose meaning is more general than "beta-Globins".
Below are MeSH descriptors whose meaning is more specific than "beta-Globins".
This graph shows the total number of publications written about "beta-Globins" by people in this website by year, and whether "beta-Globins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Globins" by people in Profiles.
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A multiplexed, allele-specific recombinase polymerase amplification assay with lateral flow readout for sickle cell disease detection. Lab Chip. 2024 08 20; 24(17):4115-4127.
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Comparisons of oxygen gradient ektacytometry parameters between sickle cell patients with or without a-thalassaemia. Br J Haematol. 2021 11; 195(4):629-633.
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Gene replacement of a-globin with ?-globin restores hemoglobin balance in ?-thalassemia-derived hematopoietic stem and progenitor cells. Nat Med. 2021 04; 27(4):677-687.
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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. PLoS Genet. 2019 12; 15(12):e1008500.
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Highly efficient editing of the??-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease. Nucleic Acids Res. 2019 09 05; 47(15):7955-7972.
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Correction of ?-thalassemia mutant by base editor in human embryos. Protein Cell. 2017 Nov; 8(11):811-822.
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Role of Heme Pocket Water in Allosteric Regulation of Ligand Reactivity in Human Hemoglobin. Biochemistry. 2016 07 26; 55(29):4005-17.
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Beta-globin gene haplotypes among cameroonians and review of the global distribution: is there a case for a single sickle mutation origin in Africa? OMICS. 2015 Mar; 19(3):171-9.
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Genetic modifiers of sickle cell anemia in the BABY HUG cohort: influence on laboratory and clinical phenotypes. Am J Hematol. 2013 Jul; 88(7):571-6.
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Recovery of small DNA fragments from serum using compaction precipitation. PLoS One. 2012; 7(12):e51863.