"Memantine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.
| Descriptor ID |
D008559
|
| MeSH Number(s) |
D02.455.426.100.050.035.500
|
| Concept/Terms |
Memantine- Memantine
- Memantin
- 1,3-Dimethyl-5-aminoadamantane
- 1-Amino-3,5-dimethyladamantane
|
Below are MeSH descriptors whose meaning is more general than "Memantine".
Below are MeSH descriptors whose meaning is more specific than "Memantine".
This graph shows the total number of publications written about "Memantine" by people in this website by year, and whether "Memantine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 4 | 1 | 5 |
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Memantine" by people in Profiles.
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Impact of Apolipoprotein E Genotype on Neurocognitive Function in Patients With Brain Metastases: An Analysis of NRG Oncology's RTOG 0614. Int J Radiat Oncol Biol Phys. 2024 Jul 01; 119(3):846-857.
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Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001. Int J Radiat Oncol Biol Phys. 2023 11 01; 117(3):571-580.
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Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2022 11 25; 11:CD011335.
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Meeting the Burden of Proof to Justify Intensity-Modulated Radiation for Brain Metastases. J Clin Oncol. 2020 10 10; 38(29):3452.
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Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. J Clin Oncol. 2020 04 01; 38(10):1019-1029.
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Interventions for cognitive problems in adults with brain cancer: A narrative review. Eur J Cancer Care (Engl). 2019 May; 28(3):e13088.
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Reply to Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma. Cancer. 2019 04 15; 125(8):1385-1386.
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Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. Cancer. 2019 02 01; 125(3):424-433.
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Radiation induces age-dependent deficits in cortical synaptic plasticity. Neuro Oncol. 2018 08 02; 20(9):1207-1214.
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Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol. 2018 04 09; 20(5):655-665.