"Quinolinic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
| Descriptor ID |
D017378
|
| MeSH Number(s) |
D03.383.725.822.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Quinolinic Acid".
Below are MeSH descriptors whose meaning is more specific than "Quinolinic Acid".
This graph shows the total number of publications written about "Quinolinic Acid" by people in this website by year, and whether "Quinolinic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinolinic Acid" by people in Profiles.
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A randomized cross-over trial to define neurophysiological correlates of AV-101 N-methyl-D-aspartate receptor blockade in healthy veterans. Neuropsychopharmacology. 2021 03; 46(4):820-827.
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Tryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae. G3 (Bethesda). 2015 May 04; 5(7):1379-89.
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Poloxamer 188 volumetrically decreases neuronal loss in the rat in a time-dependent manner. Neurosurgery. 2004 Oct; 55(4):943-8; discussion 948-9.
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Surfactant poloxamer 188-related decreases in inflammation and tissue damage after experimental brain injury in rats. J Neurosurg. 2004 Aug; 101(1 Suppl):91-6.
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Fetal striatal transplants restore electrophysiological sensitivity to dopamine in the lesioned striatum of rats with experimental Huntington's disease. J Biomed Sci. 2002 Jul-Aug; 9(4):303-10.
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Convection-enhanced selective excitotoxic ablation of the neurons of the globus pallidus internus for treatment of parkinsonism in nonhuman primates. J Neurosurg. 1999 Aug; 91(2):294-302.
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Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain. J Neurosci. 1996 May 15; 16(10):3139-53.
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Auditory P300 abnormalities and leukocyte activation in HIV infection. Otolaryngol Head Neck Surg. 1994 Jan; 110(1):53-9.
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Quinolinic acid in the cerebrospinal fluid of children with symptomatic human immunodeficiency virus type 1 disease: relationships to clinical status and therapeutic response. J Infect Dis. 1993 Dec; 168(6):1380-6.
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Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome. Arthritis Rheum. 1992 Sep; 35(9):1097-105.