"Iron Overload" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Descriptor ID |
D019190
|
| MeSH Number(s) |
C18.452.565.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Iron Overload".
Below are MeSH descriptors whose meaning is more specific than "Iron Overload".
This graph shows the total number of publications written about "Iron Overload" by people in this website by year, and whether "Iron Overload" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2023 | 2 | 0 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Iron Overload" by people in Profiles.
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Transfusion-related iron overload in survivors of childhood cancer. Blood Cells Mol Dis. 2026 Mar; 117:102977.
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Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial. Lancet Gastroenterol Hepatol. 2023 12; 8(12):1118-1128.
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Iron overload induces cerebral endothelial senescence in aged mice and in primary culture in a sex-dependent manner. Aging Cell. 2023 11; 22(11):e13977.
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Iron and a Man's Reproductive Health: the Good, the Bad, and the Ugly. Curr Urol Rep. 2018 Jun 01; 19(8):60.
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Transfusion related iron overload in pediatric oncology patients treated at a tertiary care centre and treatment with chelation therapy. Pediatr Blood Cancer. 2014 Dec; 61(12):2319-20.
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Cardiovascular function and treatment in ?-thalassemia major: a consensus statement from the American Heart Association. Circulation. 2013 Jul 16; 128(3):281-308.
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Automated T(2) * measurements using supplementary field mapping to assess cardiac iron content. J Magn Reson Imaging. 2013 Aug; 38(2):441-7.
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Adipocyte iron regulates adiponectin and insulin sensitivity. J Clin Invest. 2012 Oct; 122(10):3529-40.
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From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging. Br J Haematol. 2012 Aug; 158(3):415-8.
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Simultaneous field and R2 mapping to quantify liver iron content using autoregressive moving average modeling. J Magn Reson Imaging. 2012 May; 35(5):1125-32.