"Pyruvaldehyde" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
| Descriptor ID |
D011765
|
| MeSH Number(s) |
D02.047.644.650
|
| Concept/Terms |
Pyruvaldehyde- Pyruvaldehyde
- Methylglyoxal
- Pyruvic Aldehyde
- Aldehyde, Pyruvic
- Acetylformaldehyde
|
Below are MeSH descriptors whose meaning is more general than "Pyruvaldehyde".
Below are MeSH descriptors whose meaning is more specific than "Pyruvaldehyde".
This graph shows the total number of publications written about "Pyruvaldehyde" by people in this website by year, and whether "Pyruvaldehyde" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvaldehyde" by people in Profiles.
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Trypanosoma brucei aquaglyceroporins mediate the transport of metabolic end-products: Methylglyoxal, D-lactate, L-lactate and acetate. Biochim Biophys Acta Biomembr. 2018 11; 1860(11):2252-2261.
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Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species. Mol Carcinog. 2017 09; 56(9):2086-2103.
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The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovasc Diabetol. 2013 Apr 05; 12:58.
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Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy. Clin Biochem. 2011 Mar; 44(4):307-11.
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Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. Clin Chim Acta. 2011 Jan 30; 412(3-4):286-91.
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The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13505-10.
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A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells. J Neurochem. 2009 Jan; 108(1):273-84.
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Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats. Nutr Res. 2008 Jul; 28(7):464-71.
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Modulation of methylglyoxal and glutathione by soybean isoflavones in mild streptozotocin-induced diabetic rats. Nutr Metab Cardiovasc Dis. 2008 Nov; 18(9):618-23.
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Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem. 2007 Nov; 40(16-17):1232-9.