"Dizocilpine Maleate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects.
| Descriptor ID |
D016291
|
| MeSH Number(s) |
D02.455.426.559.847.181.384.380 D04.615.181.384.380
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dizocilpine Maleate".
Below are MeSH descriptors whose meaning is more specific than "Dizocilpine Maleate".
This graph shows the total number of publications written about "Dizocilpine Maleate" by people in this website by year, and whether "Dizocilpine Maleate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Dizocilpine Maleate" by people in Profiles.
-
Potential role of some oxidant/antioxidant status parameters in prefrontal cortex of rat brain in an experimental psychosis model and the protective effects of melatonin. Eur Rev Med Pharmacol Sci. 2014; 18(15):2137-44.
-
Visual experience-dependent maturation of correlated neuronal activity patterns in a developing visual system. J Neurosci. 2011 Jun 01; 31(22):8025-36.
-
NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic rats. Antioxid Redox Signal. 2010 Oct 01; 13(7):975-86.
-
Opioid-induced long-term potentiation in the spinal cord is a presynaptic event. J Neurosci. 2010 Mar 24; 30(12):4460-6.
-
Ionotropic glutamate receptors contribute to maintained neuronal hyperexcitability following spinal cord injury in rats. Exp Neurol. 2010 Jul; 224(1):321-4.
-
Neurochemical, behavioral and architectural changes after chronic inactivation of NMDA receptors in mice. Neurosci Lett. 2010 Jan 04; 468(2):166-71.
-
The protective effects of omega-3 fatty acids against MK-801-induced neurotoxicity in prefrontal cortex of rat. Neurochem Int. 2007 Jan; 50(1):196-202.
-
Activity-dependent decrease of excitability in rat hippocampal neurons through increases in I(h). Nat Neurosci. 2005 Nov; 8(11):1542-51.
-
Adrenomedullin in the rostral ventrolateral medulla increases arterial pressure and heart rate: roles of glutamate and nitric oxide. Am J Physiol Regul Integr Comp Physiol. 2004 Oct; 287(4):R729-34.
-
Valproate prevents the induction and the expression of MK-801 sensitization. Brain Res. 2002 Nov 08; 954(2):151-9.