"Trifluridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
| Descriptor ID |
D014271
|
| MeSH Number(s) |
D03.383.742.680.705.900 D13.570.230.855.900 D13.570.685.705.900
|
| Concept/Terms |
Trifluridine- Trifluridine
- Trifluorothymidine
- 2'-deoxy-5-(trifluoromethyl)uridine
- Trifluoridine
- 5-Trifluoromethyl-2'-deoxyuridine
- 5 Trifluoromethyl 2' deoxyuridine
|
Below are MeSH descriptors whose meaning is more general than "Trifluridine".
Below are MeSH descriptors whose meaning is more specific than "Trifluridine".
This graph shows the total number of publications written about "Trifluridine" by people in this website by year, and whether "Trifluridine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trifluridine" by people in Profiles.
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Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study. Lancet. 2023 07 01; 402(10395):41-53.
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Phase 1 study of the safety, pharmacokinetics, and preliminary efficacy of CA102N as monotherapy and in combination with trifluridine-tipiracil in patients with locally advanced or metastatic solid tumors. Invest New Drugs. 2023 02; 41(1):25-34.
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Herpetic Eye Disease Study: A Controlled Trial of Topical Corticosteroids for Herpes Simplex Stromal Keratitis. Ophthalmology. 2020 04; 127(4S):S5-S18.
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TAS-102 plus bevacizumab: a new standard for metastatic colorectal cancer? Lancet Oncol. 2020 03; 21(3):326-327.
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Leukocytoclastic vasculitis with late-onset Henoch-Sch?nlein purpura after trifluridine/tipiracil treatment. Dermatol Online J. 2018 Oct 15; 24(10).
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Trifluridine-Tipiracil for Previously Treated Metastatic Colorectal Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. Pharmacoeconomics. 2018 03; 36(3):285-288.
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Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2016 06; 77(6):1275-83.
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Photographic monitoring of herpes simplex virus keratitis during anti-inflammatory treatment. Arch Ophthalmol. 2011 Feb; 129(2):252-3.
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Slitlamp biomicroscopy and photographic image analysis of herpes simplex virus stromal keratitis. Arch Ophthalmol. 2009 Feb; 127(2):161-6.
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Phase I clinical study of three times a day oral administration of TAS-102 in patients with solid tumors. Cancer Invest. 2008 Oct; 26(8):794-9.