"Phenylenediamines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Aniline compounds that contain two amino groups. They are used as a precursor in the synthesis of HETEROCYCLIC COMPOUNDS and POLYMERS. p-Phenylenediamine is used in the manufacture of HAIR DYES and is an ALLERGEN.
| Descriptor ID |
D010655
|
| MeSH Number(s) |
D02.092.146.651 D02.092.782.258.651
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phenylenediamines".
Below are MeSH descriptors whose meaning is more specific than "Phenylenediamines".
This graph shows the total number of publications written about "Phenylenediamines" by people in this website by year, and whether "Phenylenediamines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Phenylenediamines" by people in Profiles.
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Effects of KCNQ potassium channel modulation on ventral tegmental area activity and connectivity in individuals with depression and anhedonia. Mol Psychiatry. 2025 Aug; 30(8):3686-3694.
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Effects of the KCNQ (Kv7) Channel Opener Ezogabine on Resting-State Functional Connectivity of Striatal Brain Reward Regions, Depression, and Anhedonia in Major Depressive Disorder: Results From a Randomized Controlled Trial. Biol Psychiatry. 2025 Oct 01; 98(7):568-577.
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy. Elife. 2025 Jan 06; 13.
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Removal of KCNQ2 from parvalbumin-expressing interneurons improves anti-seizure efficacy of retigabine. Exp Neurol. 2022 09; 355:114141.
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Kcnq2/Kv7.2 controls the threshold and bi-hemispheric symmetry of cortical spreading depolarization. Brain. 2021 10 22; 144(9):2863-2878.
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Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial. Am J Psychiatry. 2021 05 01; 178(5):437-446.
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Energy-stress-mediated AMPK activation inhibits ferroptosis. Nat Cell Biol. 2020 02; 22(2):225-234.
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A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nat Commun. 2020 02 06; 11(1):740.
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Centipedes subdue giant prey by blocking KCNQ channels. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):1646-1651.
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Validation of histone deacetylase 3 as a therapeutic target in castration-resistant prostate cancer. Prostate. 2018 03; 78(4):266-277.