"Cell Degranulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of losing secretory granules (SECRETORY VESICLES). This occurs, for example, in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules by EXOCYTOSIS.
| Descriptor ID |
D015550
|
| MeSH Number(s) |
G04.468.160
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cell Degranulation".
Below are MeSH descriptors whose meaning is more specific than "Cell Degranulation".
This graph shows the total number of publications written about "Cell Degranulation" by people in this website by year, and whether "Cell Degranulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2013 | 0 | 3 | 3 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 3 | 3 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Degranulation" by people in Profiles.
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Phenotypic and Functional Plasticity of CXCR6+ Peripheral Blood NK Cells. Front Immunol. 2021; 12:810080.
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Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation. Int J Mol Sci. 2021 Jul 08; 22(14).
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Lower esophageal sphincter muscle of patients with achalasia exhibits profound mast cell degranulation. Neurogastroenterol Motil. 2021 05; 33(5):e14055.
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Functional Dyspepsia and Duodenal Eosinophil Count and Degranulation: A Multiethnic US Veteran Cohort Study. Dig Dis Sci. 2021 10; 66(10):3482-3489.
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Syntaxin 3, but not syntaxin 4, is required for mast cell-regulated exocytosis, where it plays a primary role mediating compound exocytosis. J Biol Chem. 2019 03 01; 294(9):3012-3023.
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PD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse. J Allergy Clin Immunol. 2018 10; 142(4):1311-1321.e8.
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Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem. 2018 05 11; 293(19):7148-7159.
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Natural Killer Cells Response to IL-2 Stimulation Is Distinct between Ascites with the Presence or Absence of Malignant Cells in Ovarian Cancer Patients. Int J Mol Sci. 2017 May 17; 18(5).
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Randomized Controlled Crossover Trial Comparing the Impact of Sham or Intranasal Tear Neurostimulation on Conjunctival Goblet Cell Degranulation. Am J Ophthalmol. 2017 May; 177:159-168.
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NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing. J Cell Biol. 2016 Dec 19; 215(6):875-889.