"Mitomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
| Descriptor ID |
D008937
|
| MeSH Number(s) |
D02.806.400.249 D03.383.097.500 D03.633.100.473.412.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mitomycins".
Below are MeSH descriptors whose meaning is more specific than "Mitomycins".
This graph shows the total number of publications written about "Mitomycins" by people in this website by year, and whether "Mitomycins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitomycins" by people in Profiles.
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First analysis of the safety and efficacy of UGN-101 in the treatment of ureteral tumors. Urol Oncol. 2024 01; 42(1):20.e17-20.e23.
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C5 cytosine methylation at CpG sites enhances sequence selectivity of mitomycin C-DNA bonding. Biochemistry. 2000 Mar 14; 39(10):2612-8.
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Characteristics of the antitumor activity of M-16 and M-18, major metabolites of a new mitomycin C derivative KW-2149, in mice. Anticancer Drugs. 1995 Dec; 6(6):763-70.
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Necrotizing keratitis following trabeculectomy with mitomycin. Arch Ophthalmol. 1995 Jan; 113(1):19-20.
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Spontaneous and induced levels of chromosomal aberration and sister-chromatid exchange in neurofibromatosis: no evidence of chromosomal hypersensitivity. Mutat Res. 1992 Dec; 283(4):237-42.
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Phase II study of combination therapy with high-dose cisplatin, etoposide, and mitomycin in patients with advanced non-small-cell lung cancer. Am J Clin Oncol. 1992 Jun; 15(3):194-9.
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A randomized trial of two dosage schedules of mitomycin C in advanced breast carcinoma. Cancer. 1992 Jan 15; 69(2):476-81.
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A randomised comparative trial of mitozantrone/methotrexate/mitomycin C (MMM) and cyclophosphamide/methotrexate/5 FU (CMF) in the treatment of advanced breast cancer. Br J Cancer. 1991 May; 63(5):794-8.
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Primary medical therapy for operable breast cancer. Eur J Cancer Clin Oncol. 1989 Nov; 25(11):1623-7.
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Interferon alternating with chemotherapy for patients with metastatic renal cell carcinoma. Am J Clin Oncol. 1989 Aug; 12(4):350-4.