"Mitomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
| Descriptor ID |
D008937
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| MeSH Number(s) |
D02.806.400.249 D03.383.097.500 D03.633.100.473.412.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mitomycins".
Below are MeSH descriptors whose meaning is more specific than "Mitomycins".
This graph shows the total number of publications written about "Mitomycins" by people in this website by year, and whether "Mitomycins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Mitomycins" by people in Profiles.
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Characteristics of the antitumor activity of M-16 and M-18, major metabolites of a new mitomycin C derivative KW-2149, in mice. Anticancer Drugs. 1995 Dec; 6(6):763-70.
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Necrotizing keratitis following trabeculectomy with mitomycin. Arch Ophthalmol. 1995 Jan; 113(1):19-20.
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Spontaneous and induced levels of chromosomal aberration and sister-chromatid exchange in neurofibromatosis: no evidence of chromosomal hypersensitivity. Mutat Res. 1992 Dec; 283(4):237-42.
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A randomized trial of two dosage schedules of mitomycin C in advanced breast carcinoma. Cancer. 1992 Jan 15; 69(2):476-81.
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[Effect of a calcium influx blocker, verapamil, on the sensitivity of human bladder cancer cells to adriamycin and mitomycin C]. Gan To Kagaku Ryoho. 1988 May; 15(5):1727-31.
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Overcoming mitomycin C resistance with semisynthetic derivatives. Prog Clin Biol Res. 1986; 223:63-79.
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Occurrence of cytosolic protein and phosphoprotein changes in human colon tumor cells with the development of resistance to mitomycin C. Cancer Res. 1985 Sep; 45(9):4422-7.
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Heterogeneity of human colon carcinoma. Cancer Metastasis Rev. 1984; 3(3):177-91.
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Ligation and catheterization of the hepatic artery for palliative treatment of malignant hepatic tumors. J Surg Oncol. 1983 Aug; 23(4):219-22.
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Physiology of mixed leukocyte reaction suppressor factor. I. Role of cytoskeleton and protein synthesis in production and secretion. J Immunol. 1979 Mar; 122(3):1022-8.