Interleukin-12 Subunit p40
"Interleukin-12 Subunit p40" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine subunit that is a component of both interleukin-12 and interleukin-23. It binds to the INTERLEUKIN-12 SUBUNIT P35 via a disulfide bond to form interleukin-12 and to INTERLEUKIN-23 SUBUNIT P19 to form interleukin-23.
| Descriptor ID |
D053762
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| MeSH Number(s) |
D12.644.276.374.465.512.500 D12.644.276.374.465.759.249 D12.776.467.374.465.512.500 D12.776.467.374.465.759.249 D23.529.374.465.512.500 D23.529.374.465.550.249
|
| Concept/Terms |
Interleukin-12 Subunit p40- Interleukin-12 Subunit p40
- Interleukin 12 Subunit p40
- Interleukin-23 Subunit p40
- Interleukin 23 Subunit p40
- p40, Interleukin-23 Subunit
- Interleukin-12,23 p40 Subunit
- Interleukin 12,23 p40 Subunit
- p40 Subunit, Interleukin-12,23
- Interleukin-12b
- Interleukin 12b
- IL-12p40
- Interleukin-12 beta Chain
- Chain, Interleukin-12 beta
- Interleukin 12 beta Chain
- beta Chain, Interleukin-12
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-12 Subunit p40".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-12 Subunit p40".
This graph shows the total number of publications written about "Interleukin-12 Subunit p40" by people in this website by year, and whether "Interleukin-12 Subunit p40" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-12 Subunit p40" by people in Profiles.
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Identification of Low-Abundance Urinary Biomarkers in Lupus Nephritis Using Electrochemiluminescence Immunoassays. Arthritis Rheumatol. 2019 05; 71(5):744-755.
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Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. 2017 01; 152(1):206-217.e2.
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Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes. J Invest Dermatol. 2015 Sep; 135(9):2266-2272.
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The relationship between blood IL-12p40 level and melanoma progression. Int J Cancer. 2015 Apr 15; 136(8):1874-80.
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Alterations in serum MMP-8, MMP-9, IL-12p40 and IL-23 in multiple sclerosis patients treated with interferon-beta1b. Mult Scler. 2010 Jul; 16(7):801-9.
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Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent. J Exp Med. 2010 Mar 15; 207(3):535-52.
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Cytokines and angiogenic factors in patients with metastatic renal cell carcinoma treated with interferon-alpha: association of pretreatment serum levels with survival. Ann Oncol. 2009 Oct; 20(10):1682-7.
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Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. J Exp Med. 2009 Jun 08; 206(6):1227-35.
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The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritis. Arthritis Rheum. 2008 Jun; 58(6):1877-81.
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Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. J Immunol. 2008 May 01; 180(9):6000-9.