"Quinacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
| Descriptor ID |
D011796
|
| MeSH Number(s) |
D03.633.300.046.250.760
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Quinacrine".
Below are MeSH descriptors whose meaning is more specific than "Quinacrine".
This graph shows the total number of publications written about "Quinacrine" by people in this website by year, and whether "Quinacrine" was a major or minor topic of these publications.
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Below are the most recent publications written about "Quinacrine" by people in Profiles.
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First-in-Human Phase 1b Trial of Quinacrine Plus Capecitabine in Patients With Refractory Metastatic Colorectal Cancer. Clin Colorectal Cancer. 2021 03; 20(1):e43-e52.
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Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma. Am J Physiol Lung Cell Mol Physiol. 2009 Sep; 297(3):L411-9.
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Incidence of sperm with two fluorescent bodies in men with impaired fertility. Fertil Steril. 1992 Feb; 57(2):402-8.
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Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord. J Pharmacol Exp Ther. 1988 Nov; 247(2):473-80.
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Fluorescent body distribution in spermatozoa in the male with exclusively female offspring. Fertil Steril. 1988 Apr; 49(4):670-5.
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Bradykinin stimulation of oxidative metabolism in renal cortical tubules from rabbit. Possible role of arachidonic acid. J Clin Invest. 1985 Nov; 76(5):1812-8.
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Somatic cell genetic assignment of peptidase C and the Rh linkage group to chromosome A-1 in man. Science. 1972 Jun 30; 176(4042):1429-31.
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Murine malaria: the role of humoral factors and macrophages in destruction of parasitized erythrocytes. J Immunol. 1971 Jul; 107(1):212-21.