"Tacrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
| Descriptor ID |
D013619
|
| MeSH Number(s) |
D03.633.300.046.250.900
|
| Concept/Terms |
Tacrine- Tacrine
- 9-Amino-1,2,3,4-Tetrahydroacridine
- 1,2,3,4-Tetrahydro-9-acridinamine
- Tetrahydroaminoacridine
- 1,2,3,4-Tetrahydroaminoacridine
|
Below are MeSH descriptors whose meaning is more general than "Tacrine".
Below are MeSH descriptors whose meaning is more specific than "Tacrine".
This graph shows the total number of publications written about "Tacrine" by people in this website by year, and whether "Tacrine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tacrine" by people in Profiles.
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Clinical use of cholinomimetic agents: a review. J Head Trauma Rehabil. 2002 Aug; 17(4):314-21.
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Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001 Jul-Aug; 12(4):295-300.
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Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities. Pharmacol Biochem Behav. 1998 Jun; 60(2):377-86.
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Huperzine A, a novel promising acetylcholinesterase inhibitor. Neuroreport. 1996 Dec 20; 8(1):97-101.
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Ethological study of the effects of tetrahydroaminoacridine (THA) on social recognition in rats. Psychopharmacology (Berl). 1994 May; 114(4):644-50.