Group VI Phospholipases A2
"Group VI Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A calcium-independent phospholipase A2 group that may play a role in membrane phospholipid remodeling and homeostasis by controling the levels of PHOSPHATIDYLCHOLINE in mammalian cell membranes.
| Descriptor ID |
D054522
|
| MeSH Number(s) |
D08.811.277.352.100.680.750.937.300.249
|
| Concept/Terms |
Group VI Phospholipases A2- Group VI Phospholipases A2
- Phospholipases A2, Group VI
- iPLA(2)-1
- iPLA(2)-2
- Group VI Phospholipase A(2)
- Group VI Phospholipase A2
|
Below are MeSH descriptors whose meaning is more general than "Group VI Phospholipases A2".
Below are MeSH descriptors whose meaning is more specific than "Group VI Phospholipases A2".
This graph shows the total number of publications written about "Group VI Phospholipases A2" by people in this website by year, and whether "Group VI Phospholipases A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 2 | 3 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Group VI Phospholipases A2" by people in Profiles.
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The role of the PLA2G6 gene in neurodegenerative diseases. Ageing Res Rev. 2023 08; 89:101957.
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Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14). Elife. 2023 01 16; 12.
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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nat Commun. 2018 11 14; 9(1):4774.
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PLA2G6-associated neurodegeneration: New insights into brain abnormalities and disease progression. Parkinsonism Relat Disord. 2019 04; 61:179-186.
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Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study. Hum Mol Genet. 2018 08 15; 27(16):2940-2953.
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Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to a-Synuclein Gain. Cell Metab. 2018 10 02; 28(4):605-618.e6.
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Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis. 2013 Apr; 34(4):885-92.
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Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations. Am J Pathol. 2008 Feb; 172(2):406-16.