Lambert-Eaton Myasthenic Syndrome
"Lambert-Eaton Myasthenic Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
Descriptor ID |
D015624
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MeSH Number(s) |
C04.588.614.550.225 C04.730.856.225 C10.114.468 C10.574.781.500 C10.668.758.450 C20.111.258.350
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Concept/Terms |
Lambert-Eaton Myasthenic Syndrome- Lambert-Eaton Myasthenic Syndrome
- Lambert Eaton Myasthenic Syndrome
- Eaton-Lambert Myasthenic Syndrome
- Eaton Lambert Myasthenic Syndrome
- Myasthenic Syndrome, Eaton-Lambert
- Syndrome, Eaton-Lambert Myasthenic
- Myasthenic Syndrome, Lambert-Eaton
- Myasthenic Syndrome, Lambert Eaton
- Syndrome, Lambert-Eaton Myasthenic
- Myopathic-Myasthenic Syndrome of Lambert-Eaton
- Lambert-Eaton Myopathic-Myasthenic Syndrome
- Lambert-Eaton Myopathic-Myasthenic Syndromes
- Lambert-Eaton Syndrome
- Lambert Eaton Syndrome
- Syndrome, Lambert-Eaton
- Myasthenic-Myopathic Syndrome of Lambert-Eaton
- Lambert-Eaton Myasthenic-Myopathic Syndrome
- Lambert-Eaton Myasthenic-Myopathic Syndromes
- Myasthenic Myopathic Syndrome of Lambert Eaton
- Myopathic-Myasthenic Syndrome of Eaton-Lambert
- Eaton-Lambert Myopathic-Myasthenic Syndrome
- Eaton-Lambert Myopathic-Myasthenic Syndromes
- Myopathic Myasthenic Syndrome of Eaton Lambert
- Eaton-Lambert Syndrome
- Eaton Lambert Syndrome
- Syndrome, Eaton-Lambert
- Myasthenic-Myopathic Syndrome of Eaton-Lambert
- Eaton-Lambert Myasthenic-Myopathic Syndrome
- Myasthenic Myopathic Syndrome of Eaton Lambert
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Below are MeSH descriptors whose meaning is more general than "Lambert-Eaton Myasthenic Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Lambert-Eaton Myasthenic Syndrome".
This graph shows the total number of publications written about "Lambert-Eaton Myasthenic Syndrome" by people in this website by year, and whether "Lambert-Eaton Myasthenic Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 2 | 0 | 2 |
2006 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2018 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lambert-Eaton Myasthenic Syndrome" by people in Profiles.
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Validation of the triple timed up-and-go test in Lambert-Eaton myasthenia. Muscle Nerve. 2019 09; 60(3):292-298.
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Reply. Muscle Nerve. 2018 05; 57(5):E130-E131.
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3,4-diaminopyridine base effectively treats the weakness of Lambert-Eaton myasthenia. Muscle Nerve. 2018 04; 57(4):561-568.
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Paraneoplastic syndromes in patients with laryngeal neuroendocrine carcinomas: clinical manifestations and prognostic significance. Eur Arch Otorhinolaryngol. 2016 Mar; 273(3):533-6.
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Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy. Am J Hum Genet. 2014 Sep 04; 95(3):332-9.
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A 7-year-old child with chronic droopy eyes, weakness in head-neck control, and an abnormal gait. Semin Pediatr Neurol. 2014 Jun; 21(2):111-3.
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Lambert-eaton myasthenic syndrome in a patient with small-cell lung cancer. Clin Lung Cancer. 2006 Jan; 7(4):282-4.
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Literature review of the usefulness of repetitive nerve stimulation and single fiber EMG in the electrodiagnostic evaluation of patients with suspected myasthenia gravis or Lambert-Eaton myasthenic syndrome. Muscle Nerve. 2001 Sep; 24(9):1239-47.
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Practice parameter for repetitive nerve stimulation and single fiber EMG evaluation of adults with suspected myasthenia gravis or Lambert-Eaton myasthenic syndrome: summary statement. Muscle Nerve. 2001 Sep; 24(9):1236-8.
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Paraneoplastic syndromes. Neurology. 1993 Jan; 43(1):236.