Lambert-Eaton Myasthenic Syndrome

"Lambert-Eaton Myasthenic Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)


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This graph shows the total number of publications written about "Lambert-Eaton Myasthenic Syndrome" by people in this website by year, and whether "Lambert-Eaton Myasthenic Syndrome" was a major or minor topic of these publications.
Bar chart showing 8 publications over 5 distinct years, with a maximum of 2 publications in 2001 and 2014 and 2018
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