Receptor, Serotonin, 5-HT2A
"Receptor, Serotonin, 5-HT2A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.
| Descriptor ID |
D044402
|
| MeSH Number(s) |
D12.776.543.750.670.800.200.100 D12.776.543.750.695.800.200.100 D12.776.543.750.720.850.200.100
|
| Concept/Terms |
Receptor, Serotonin, 5-HT2A- Receptor, Serotonin, 5-HT2A
- 5-HT2A Receptor
- 5 HT2A Receptor
- Receptor, 5-HT2A
- Serotonin 2A Receptors
- Receptors, Serotonin 2A
- Serotonin 2A Receptor
- 5-HT(2A) Receptor
- Receptor, Serotonin 2A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.670.800.200.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.695.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.695.800.200.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.720.850.200.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT2A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2A" by people in Profiles.
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Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT2C Receptor and Dual 5-HT2C/5-HT2A Receptor Modulators. J Med Chem. 2023 07 27; 66(14):9992-10009.
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Pimavanserin reverses multiple measures of anxiety in a rodent model of post-traumatic stress disorder. Eur J Pharmacol. 2023 Jan 15; 939:175437.
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Sexual Functioning in Adolescents With Major Depressive Disorder: A Prospective Study. J Clin Psychiatry. 2021 10 05; 82(6).
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Inverse agonists of the 5-HT2A receptor reduce nicotine withdrawal signs in rats. Neurosci Lett. 2019 11 20; 713:134524.
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Association of TPH1 and serotonin transporter genotypes with treatment response for suicidal ideation: a preliminary study. Eur Arch Psychiatry Clin Neurosci. 2020 Aug; 270(5):633-642.
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Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for?Subsequent Basal Cell Carcinoma. J Invest Dermatol. 2019 09; 139(9):2042-2045.e8.
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Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction. PLoS One. 2018; 13(8):e0203137.
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Synthesis and activity of functionalizable derivatives of the serotonin (5-HT) 5-HT2A receptor (5-HT2AR) antagonist M100907. Bioorg Med Chem Lett. 2018 05 01; 28(8):1381-1385.
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The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection. Invest Ophthalmol Vis Sci. 2018 01 01; 59(1):462-471.
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Novel Bivalent 5-HT2A Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo. ACS Chem Neurosci. 2018 03 21; 9(3):514-521.