"Polymyositis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)
| Descriptor ID |
D017285
|
| MeSH Number(s) |
C05.651.594.819 C10.668.491.562.575
|
| Concept/Terms |
Polymyositis- Polymyositis
- Polymyositides
- Myositis, Multiple
- Multiple Myositis
- Myositides, Multiple
Polymyositis, Idiopathic- Polymyositis, Idiopathic
- Idiopathic Polymyositides
- Idiopathic Polymyositis
- Polymyositides, Idiopathic
|
Below are MeSH descriptors whose meaning is more general than "Polymyositis".
Below are MeSH descriptors whose meaning is more specific than "Polymyositis".
This graph shows the total number of publications written about "Polymyositis" by people in this website by year, and whether "Polymyositis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 2 | 1 | 3 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polymyositis" by people in Profiles.
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Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation. Arthritis Rheumatol. 2023 06; 75(6):1021-1027.
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Accumulation of autophagosome cargo protein p62 is common in idiopathic inflammatory myopathies. Clin Exp Rheumatol. 2021 Mar-Apr; 39(2):351-356.
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Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis. Ann Rheum Dis. 2020 09; 79(9):1234-1242.
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Polymyositis has minimal effect on primary total knee or hip arthroplasty outcomes. Clin Rheumatol. 2020 Mar; 39(3):823-830.
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Muscle endurance deficits in myositis patients despite normal manual muscle testing scores. Muscle Nerve. 2019 01; 59(1):70-75.
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Anti-NT5C1A autoantibodies are associated with more severe disease in patients with juvenile myositis. Ann Rheum Dis. 2018 05; 77(5):714-719.
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Overlapping features of polymyositis and inclusion body myositis in HIV-infected patients. Neurology. 2017 Apr 11; 88(15):1454-1460.
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Thigh muscle MRI in immune-mediated necrotising myopathy: extensive oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity. Ann Rheum Dis. 2017 04; 76(4):681-687.
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Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Ann Rheum Dis. 2016 Aug; 75(8):1558-66.
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Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. Genes Immun. 2015 Oct; 16(7):470-80.