"Malates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of malic acid (the structural formula: (COO-)2CH2CHOH), including its salts and esters.
| Descriptor ID |
D008293
|
| MeSH Number(s) |
D02.241.081.337.463 D02.241.511.505
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Malates".
Below are MeSH descriptors whose meaning is more specific than "Malates".
This graph shows the total number of publications written about "Malates" by people in this website by year, and whether "Malates" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Malates" by people in Profiles.
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Targeting c-Myc transactivation by LMNA inhibits tRNA processing essential for malate-aspartate shuttle and tumour progression. Clin Transl Med. 2024 05; 14(5):e1680.
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Therapeutic targeting of FUBP3 phase separation by GATA2-AS1 inhibits malate-aspartate shuttle and neuroblastoma progression via modulating SUZ12 activity. Oncogene. 2023 09; 42(36):2673-2687.
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Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. Am J Hum Genet. 2017 Jan 05; 100(1):151-159.
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Localization of the nucleic acid channel regulatory subunit, cytosolic malate dehydrogenase. J Membr Biol. 2008 Nov-Dec; 226(1-3):1-8.
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Effect of different organic acids (citric, malic and ascorbic) on intragastric urease activity. Aliment Pharmacol Ther. 2005 May 01; 21(9):1145-8.
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Muscle mitochondrial ATP production in progressive supranuclear palsy. J Neurochem. 1994 Apr; 62(4):1631-4.
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Hepatocyte heterogeneity in uptake and metabolism of malate and related dicarboxylates in perfused rat liver. Eur J Biochem. 1991 Jan 01; 195(1):121-9.