"Ethambutol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)
Descriptor ID |
D004977
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MeSH Number(s) |
D02.092.782.258.368.265
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ethambutol".
Below are MeSH descriptors whose meaning is more specific than "Ethambutol".
This graph shows the total number of publications written about "Ethambutol" by people in this website by year, and whether "Ethambutol" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2000 | 1 | 0 | 1 |
2002 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2017 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ethambutol" by people in Profiles.
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Esophageal Tuberculosis - A Mass of Confusion. Am J Med. 2020 10; 133(10):e589-e590.
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[Tuberculosis]. Internist (Berl). 2019 Nov; 60(11):1155-1175.
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Ethambutol optic neuropathy. Curr Opin Ophthalmol. 2017 Nov; 28(6):545-551.
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Spread of extensively drug-resistant tuberculosis in KwaZulu-Natal province, South Africa. PLoS One. 2011; 6(5):e17513.
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Decreased retinal nerve fibre layer thickness detected by optical coherence tomography in patients with ethambutol-induced optic neuropathy. Br J Ophthalmol. 2007 Jul; 91(7):895-7.
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Pharmacokinetics of ethambutol in children and adults with tuberculosis. Int J Tuberc Lung Dis. 2004 Nov; 8(11):1360-7.
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Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine. J Infect. 2002 Apr; 44(3):201-3.
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Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2000 Feb; 44(2):326-36.
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Outpatient management of tuberculosis. Am Fam Physician. 1996 Apr; 53(5):1579-94.
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Recurrent disseminated infection with Mycobacterium avium complex identified in tissues by molecular analysis. Clin Infect Dis. 1996 Apr; 22(4):714-15.