Deoxyribonucleases, Type II Site-Specific
"Deoxyribonucleases, Type II Site-Specific" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.
| Descriptor ID |
D015252
|
| MeSH Number(s) |
D08.811.150.280.260 D08.811.277.352.335.350.300.260 D08.811.277.352.355.325.300.260
|
| Concept/Terms |
Deoxyribonucleases, Type II Site-Specific- Deoxyribonucleases, Type II Site-Specific
- Deoxyribonucleases, Type II Site Specific
- Deoxyribonucleases, Type II, Site Specific
- Deoxyribonucleases, Type II, Site-Specific
- Type II Site Specific Deoxyribonucleases
- Type II Site-Specific Deoxyribonucleases
- Restriction Endonucleases, Type II
- DNase, Site Specific, Type II
- Site-Specific DNase, Type II
- Site Specific DNase, Type II
- Type II Site Specific DNase
- Type II Site-Specific DNase
- DNase, Site-Specific, Type II
- Type II Restriction Enzymes
- DNA Restriction Enzymes, Type II
|
Below are MeSH descriptors whose meaning is more general than "Deoxyribonucleases, Type II Site-Specific".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonucleases, Type II Site-Specific".
This graph shows the total number of publications written about "Deoxyribonucleases, Type II Site-Specific" by people in this website by year, and whether "Deoxyribonucleases, Type II Site-Specific" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 |
| 1996 | 3 | 0 | 3 |
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Deoxyribonucleases, Type II Site-Specific" by people in Profiles.
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A Rad51-independent pathway promotes single-strand template repair in gene editing. PLoS Genet. 2020 10; 16(10):e1008689.
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Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 ?. Nucleic Acids Res. 2020 02 20; 48(3):1466-1478.
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Highly efficient one-step scarless protein tagging by type IIS restriction endonuclease-mediated precision cloning. Biochem Biophys Res Commun. 2017 08 12; 490(1):8-16.
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DNA double-strand breaks activate ATM independent of mitochondrial dysfunction in A549 cells. Free Radic Biol Med. 2014 Oct; 75:30-9.
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Genetic modifiers of sickle cell anemia in the BABY HUG cohort: influence on laboratory and clinical phenotypes. Am J Hematol. 2013 Jul; 88(7):571-6.
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Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique. Epigenetics. 2012 Dec 01; 7(12):1368-78.
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Preferential repair of DNA double-strand break at the active gene in vivo. J Biol Chem. 2012 Oct 19; 287(43):36414-22.
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Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res. 2012 Aug; 40(15):e117.
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Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data. Eur J Cancer. 2009 Dec; 45(18):3271-81.
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SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY). 2009 Jan 15; 1(1):109-21.