"Paraparesis, Spastic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mild or moderate loss of motor function accompanied by spasticity in the lower extremities. This condition is a manifestation of CENTRAL NERVOUS SYSTEM DISEASES that cause injury to the motor cortex or descending motor pathways.
| Descriptor ID |
D020336
|
| MeSH Number(s) |
C10.597.636.500.500 C23.888.592.643.500.500
|
| Concept/Terms |
Paraparesis, Spastic- Paraparesis, Spastic
- Parapareses, Spastic
- Spastic Parapareses
- Spastic Lower Extremity Weakness
- Spastic Paraparesis
- Lower Extremity Weakness, Spastic
|
Below are MeSH descriptors whose meaning is more general than "Paraparesis, Spastic".
Below are MeSH descriptors whose meaning is more specific than "Paraparesis, Spastic".
This graph shows the total number of publications written about "Paraparesis, Spastic" by people in this website by year, and whether "Paraparesis, Spastic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Paraparesis, Spastic" by people in Profiles.
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Bi-allelic SNAPC4 variants dysregulate global alternative splicing and lead to neuroregression and progressive spastic paraparesis. Am J Hum Genet. 2023 04 06; 110(4):663-680.
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Novel insertional presenilin 1 mutation causing Alzheimer disease with spastic paraparesis. Neurology. 2004 May 25; 62(10):1865-8.
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Cervicothoracic extradural arachnoid cyst: possible association with obstetric brachial plexus palsy. J Child Neurol. 2002 Oct; 17(10):770-2.