"Lyme Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
| Descriptor ID |
D008193
|
| MeSH Number(s) |
C01.252.400.155.569 C01.252.400.825.480 C01.252.847.193.569
|
| Concept/Terms |
Lyme Disease- Lyme Disease
- Disease, Lyme
- B. burgdorferi Infection
- B. burgdorferi Infections
- Lyme Borreliosis
- Borreliosis, Lyme
- Borrelia burgdorferi Infection
- Borrelia burgdorferi Infections
|
Below are MeSH descriptors whose meaning is more general than "Lyme Disease".
Below are MeSH descriptors whose meaning is more specific than "Lyme Disease".
This graph shows the total number of publications written about "Lyme Disease" by people in this website by year, and whether "Lyme Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2018 | 3 | 0 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2022 | 5 | 0 | 5 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Lyme Disease" by people in Profiles.
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Biophysical and biochemical characterization of a recombinant Lyme disease vaccine antigen, CspZ-YA. Int J Biol Macromol. 2024 Feb; 259(Pt 2):129295.
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Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway. J Immunol. 2023 06 01; 210(11):1761-1770.
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Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection. Front Immunol. 2022; 13:1012824.
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Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein. Front Cell Infect Microbiol. 2022; 12:991689.
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Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights. Expert Rev Vaccines. 2022 10; 21(10):1405-1417.
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CspZ FH-Binding Sites as Epitopes Promote Antibody-Mediated Lyme Borreliae Clearance. Infect Immun. 2022 07 21; 90(7):e0006222.
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Characterization of Immunological Responses to Borrelia Immunogenic Protein A (BipA), a Species-Specific Antigen for North American Tick-Borne Relapsing Fever. Microbiol Spectr. 2022 06 29; 10(3):e0172221.
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The Factor H-Binding Site of CspZ as a Protective Target against Multistrain, Tick-Transmitted Lyme Disease. Infect Immun. 2020 04 20; 88(5).
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Antibodies to Borrelia turicatae in Experimentally Infected Dogs Cross-React with Borrelia burgdorferi Serologic Assays. J Clin Microbiol. 2019 09; 57(9).
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Usefulness of Routine Lyme Screening in Patients with Uveitis. Ophthalmology. 2019 12; 126(12):1726-1728.