Glial Cell Line-Derived Neurotrophic Factor
"Glial Cell Line-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
Descriptor ID |
D051100
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MeSH Number(s) |
D12.644.276.860.381.500 D12.776.467.860.381.500 D12.776.631.600.381.500 D23.529.850.381.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glial Cell Line-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Glial Cell Line-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Glial Cell Line-Derived Neurotrophic Factor" by people in this website by year, and whether "Glial Cell Line-Derived Neurotrophic Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 2 | 2 |
1999 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 2 | 0 | 2 |
2010 | 1 | 1 | 2 |
2012 | 1 | 1 | 2 |
2013 | 0 | 1 | 1 |
2017 | 2 | 1 | 3 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glial Cell Line-Derived Neurotrophic Factor" by people in Profiles.
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Regulation of GDNF expression in Sertoli cells. Reproduction. 2019 03; 157(3):R95-R107.
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Testicular endothelial cells are a critical population in the germline stem cell niche. Nat Commun. 2018 10 22; 9(1):4379.
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Solid pseudopapillary tumor of pancreas: A case report and review of genetic features. Pediatr Blood Cancer. 2018 06; 65(6):e26980.
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A preliminary evaluation of glial cell line-derived neurotrophic factor (GDNF) levels in cerebrospinal fluid across various gestational ages and clinical conditions of the neonate. Int J Dev Neurosci. 2018 Apr; 65:61-65.
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Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network. Stem Cells. 2017 06; 35(6):1554-1565.
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The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells. Stem Cells Dev. 2017 04 15; 26(8):585-598.
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Neurotrophic factor GDNF promotes survival of salivary stem cells. J Clin Invest. 2014 Aug; 124(8):3364-77.
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Spermatogonial behavior in rats during radiation-induced arrest and recovery after hormone suppression. Reproduction. 2013 Oct; 146(4):363-76.
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Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. J Biol Chem. 2013 Jul 19; 288(29):20843-20855.
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Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. Dev Biol. 2013 May 01; 377(1):188-201.