Glial Cell Line-Derived Neurotrophic Factor
"Glial Cell Line-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
| Descriptor ID |
D051100
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| MeSH Number(s) |
D12.644.276.860.381.500 D12.776.467.860.381.500 D12.776.631.600.381.500 D23.529.850.381.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glial Cell Line-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Glial Cell Line-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Glial Cell Line-Derived Neurotrophic Factor" by people in this website by year, and whether "Glial Cell Line-Derived Neurotrophic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glial Cell Line-Derived Neurotrophic Factor" by people in Profiles.
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Regulation of GDNF expression in Sertoli cells. Reproduction. 2019 03; 157(3):R95-R107.
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Solid pseudopapillary tumor of pancreas: A case report and review of genetic features. Pediatr Blood Cancer. 2018 06; 65(6):e26980.
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A preliminary evaluation of glial cell line-derived neurotrophic factor (GDNF) levels in cerebrospinal fluid across various gestational ages and clinical conditions of the neonate. Int J Dev Neurosci. 2018 Apr; 65:61-65.
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Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network. Stem Cells. 2017 06; 35(6):1554-1565.
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The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells. Stem Cells Dev. 2017 04 15; 26(8):585-598.
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Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. J Biol Chem. 2013 Jul 19; 288(29):20843-20855.
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A phase II evaluation of motesanib (AMG 706) in the treatment of persistent or recurrent ovarian, fallopian tube and primary peritoneal carcinomas: a Gynecologic Oncology Group study. Gynecol Oncol. 2013 Apr; 129(1):86-91.
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COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. Development. 2012 Jul; 139(13):2330-9.
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Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia. Toxicology. 2012 Sep 04; 299(1):10-9.
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An immunoprotective privilege of corneal epithelial stem cells against Th17 inflammatory stress by producing glial cell-derived neurotrophic factor. Stem Cells. 2010 Dec; 28(12):2172-81.