Glial Cell Line-Derived Neurotrophic Factor
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Glial Cell Line-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
    
			
			
				
				
					
						| Descriptor ID | D051100 | 
					
						| MeSH Number(s) | D12.644.276.860.381.500 D12.776.467.860.381.500 D12.776.631.600.381.500 D23.529.850.381.500 | 
					
						| Concept/Terms |  | 
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "Glial Cell Line-Derived Neurotrophic Factor".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Glial Cell Line-Derived Neurotrophic Factor".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Glial Cell Line-Derived Neurotrophic Factor" by people in this website by year, and whether "Glial Cell Line-Derived Neurotrophic Factor" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1998 | 0 | 2 | 2 | 
| 1999 | 0 | 1 | 1 | 
| 2002 | 0 | 1 | 1 | 
| 2003 | 0 | 1 | 1 | 
| 2007 | 0 | 1 | 1 | 
| 2008 | 2 | 0 | 2 | 
| 2010 | 1 | 1 | 2 | 
| 2012 | 1 | 1 | 2 | 
| 2013 | 0 | 1 | 1 | 
| 2017 | 2 | 1 | 3 | 
| 2018 | 1 | 0 | 1 | 
| 2019 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Glial Cell Line-Derived Neurotrophic Factor" by people in Profiles.
						
					
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								Regulation of GDNF expression in Sertoli cells. Reproduction. 2019 03; 157(3):R95-R107. 
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								Testicular endothelial cells are a critical population in the germline stem cell niche. Nat Commun. 2018 10 22; 9(1):4379. 
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								Solid pseudopapillary tumor of pancreas: A case report and review of genetic features. Pediatr Blood Cancer. 2018 06; 65(6):e26980. 
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								A preliminary evaluation of glial cell line-derived neurotrophic factor (GDNF) levels in cerebrospinal fluid across various gestational ages and clinical conditions of the neonate. Int J Dev Neurosci. 2018 Apr; 65:61-65. 
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								Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network. Stem Cells. 2017 06; 35(6):1554-1565. 
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								The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells. Stem Cells Dev. 2017 04 15; 26(8):585-598. 
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								Neurotrophic factor GDNF promotes survival of salivary stem cells. J Clin Invest. 2014 Aug; 124(8):3364-77. 
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								Spermatogonial behavior in rats during radiation-induced arrest and recovery after hormone suppression. Reproduction. 2013 Oct; 146(4):363-76. 
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								Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. J Biol Chem. 2013 Jul 19; 288(29):20843-20855. 
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								Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. Dev Biol. 2013 May 01; 377(1):188-201.