"Ristocetin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic mixture of two components, A and B, obtained from Nocardia lurida (or the same substance produced by any other means). It is no longer used clinically because of its toxicity. It causes platelet agglutination and blood coagulation and is used to assay those functions in vitro.
| Descriptor ID |
D012310
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| MeSH Number(s) |
D09.400.420.800 D12.644.233.697
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ristocetin".
Below are MeSH descriptors whose meaning is more specific than "Ristocetin".
This graph shows the total number of publications written about "Ristocetin" by people in this website by year, and whether "Ristocetin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ristocetin" by people in Profiles.
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N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress. J Biol Chem. 2012 Apr 27; 287(18):14579-85.
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N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice. J Clin Invest. 2011 Feb; 121(2):593-603.
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Enhanced platelet adhesion and aggregation by endothelial cell-derived unusually large multimers of von Willebrand factor. Biorheology. 2006; 43(5):681-91.
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The alpha1 helix-beta13 strand spanning Leu214 to Val229 of platelet glycoprotein Ibalpha facilitates the interaction with von Willebrand factor: evidence from characterization of the epitope of monoclonal antibody AP1. Blood. 2004 Dec 15; 104(13):3971-8.
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Platelet aggregation by membrane-expressed A1 domains of von Willebrand Factor is dependent on residues Asp 560 and Gly 561. Biochem Biophys Res Commun. 2003 Mar 21; 302(4):873-7.
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Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers. Blood. 2002 Jun 01; 99(11):3971-7.
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Measurement of the binding forces between von Willebrand factor and variants of platelet glycoprotein Ibalpha using optical tweezers. Lasers Surg Med. 2002; 30(4):306-12.
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Increased von Willebrand factor binding to platelets in single episode and recurrent types of thrombotic thrombocytopenic purpura. Am J Hematol. 1998 Apr; 57(4):293-302.
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Activation of human platelets by the membrane-expressed A1 domain of von Willebrand factor. Blood. 1997 Dec 01; 90(11):4425-37.
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Familial infantile thrombotic thrombocytopenic purpura. J Pediatr Hematol Oncol. 1996 May; 18(2):171-4.