"Phenindione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Descriptor ID |
D010630
|
MeSH Number(s) |
D02.455.426.559.847.486.487.750 D04.615.486.487.750
|
Concept/Terms |
Phenindione- Phenindione
- Phenylindanedione
- 2-Phenyl-1,3-indandione
- 2 Phenyl 1,3 indandione
|
Below are MeSH descriptors whose meaning is more general than "Phenindione".
Below are MeSH descriptors whose meaning is more specific than "Phenindione".
This graph shows the total number of publications written about "Phenindione" by people in this website by year, and whether "Phenindione" was a major or minor topic of these publications.
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Below are the most recent publications written about "Phenindione" by people in Profiles.
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Inhibition of renal NQO1 activity by dicoumarol suppresses nitroreduction of aristolochic acid I and attenuates its nephrotoxicity. Toxicol Sci. 2011 Aug; 122(2):288-96.
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Mechanism of action of anticoagulants: correlation between the inhibition of prothrombin synthesis and the regeneration of vitamin K1 from vitamin K1 epoxide. J Pharmacol Exp Ther. 1977 Jun; 201(3):541-6.