"Chediak-Higashi Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.
| Descriptor ID |
D002609
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| MeSH Number(s) |
C15.378.553.774.257 C20.673.774.257
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| Concept/Terms |
Chediak-Higashi Syndrome- Chediak-Higashi Syndrome
- Chediak Higashi Syndrome
- Syndrome, Chediak-Higashi
- Oculocutaneous Albinism with Leukocyte Defect
- Chediak-Steinbrinck-Higashi Syndrome
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Below are MeSH descriptors whose meaning is more general than "Chediak-Higashi Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Chediak-Higashi Syndrome".
This graph shows the total number of publications written about "Chediak-Higashi Syndrome" by people in this website by year, and whether "Chediak-Higashi Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chediak-Higashi Syndrome" by people in Profiles.
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Fludarabine and once-daily intravenous busulfan for allogeneic bone marrow transplantation for Chediak-Higashi syndrome. J Pediatr Hematol Oncol. 2003 Oct; 25(10):824-6.
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Nidogen/entactin (Nid) maps to the proximal end of mouse chromosome 13 linked to beige (bg) and identifies a new region of homology between mouse and human chromosomes. Genomics. 1991 Feb; 9(2):401-3.
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The accelerated phase of Chediak-Higashi syndrome. An expression of the virus-associated hemophagocytic syndrome? Cancer. 1985 Aug 01; 56(3):524-30.