"2,3-Diphosphoglycerate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
| Descriptor ID |
D019794
|
| MeSH Number(s) |
D02.241.081.844.387.388.175 D02.241.511.902.387.388.175 D02.705.400.140.175 D09.811.366.388.175
|
| Concept/Terms |
2,3-Diphosphoglycerate- 2,3-Diphosphoglycerate
- 2,3 Diphosphoglycerate
- 2,3-DPG
- Glycerate 2,3-Bisphosphate
- 2,3-Bisphosphate, Glycerate
- 2,3-Bisphosphoglycerate
- 2,3 Bisphosphoglycerate
|
Below are MeSH descriptors whose meaning is more general than "2,3-Diphosphoglycerate".
Below are MeSH descriptors whose meaning is more specific than "2,3-Diphosphoglycerate".
This graph shows the total number of publications written about "2,3-Diphosphoglycerate" by people in this website by year, and whether "2,3-Diphosphoglycerate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "2,3-Diphosphoglycerate" by people in Profiles.
-
Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming. PLoS Biol. 2021 06; 19(6):e3001239.
-
Serial assessment of biochemical parameters of red cell preparations to evaluate safety for neonatal transfusions. Indian J Med Res. 2010 Dec; 132:715-20.
-
Regulation of the glycophorin C-protein 4.1 membrane-to-skeleton bridge and evaluation of its contribution to erythrocyte membrane stability. J Biol Chem. 2001 Jun 22; 276(25):22223-30.
-
The major phosphorylation site of nucleophosmin (B23) is phosphorylated by a nuclear kinase II. Biochem J. 1990 Sep 01; 270(2):549-52.
-
Vanadium(IV)-stimulated hydrolysis of 2,3-diphosphoglycerate. Arch Biochem Biophys. 1989 May 01; 270(2):489-94.
-
The catalytic bimodality of mammalian phosphoglycerate mutase. J Biol Chem. 1986 Sep 25; 261(27):12715-21.