"Clotrimazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.
| Descriptor ID |
D003022
|
| MeSH Number(s) |
D03.383.129.308.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Clotrimazole".
Below are MeSH descriptors whose meaning is more specific than "Clotrimazole".
This graph shows the total number of publications written about "Clotrimazole" by people in this website by year, and whether "Clotrimazole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clotrimazole" by people in Profiles.
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Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death. Am J Physiol Cell Physiol. 2012 Nov 15; 303(10):C1070-8.
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Persistent and recurrent tinea corporis in children treated with combination antifungal/ corticosteroid agents. Pediatrics. 2003 Jan; 111(1):201-3.
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Comparison of once- and twice-daily naftifine cream regimens with twice-daily clotrimazole in the treatment of tinea pedis. J Am Acad Dermatol. 1990 Jun; 22(6 Pt 1):1116-7.
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Three-day treatment with butoconazole vaginal suppositories for vulvovaginal candidiasis. J Reprod Med. 1986 Feb; 31(2):131-2.
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Comparison of econazole and clotrimazole in the treatment of vulvovaginal candidiasis. Obstet Gynecol. 1980 Jul; 56(1):121-3.